Antiviral effect of octyl gallate against DNA and RNA viruses (Record no. 44948)

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fixed length control field 02128nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140636.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-10716
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245 10 - TITLE STATEMENT
Title Antiviral effect of octyl gallate against DNA and RNA viruses
490 0# - SERIES STATEMENT
Volume/sequential designation Antiviral Research, 73(2), p.85-91, 2007
520 3# - SUMMARY, ETC.
Summary, etc. The effects of gallic acid (3,4,5-trihydroxybenzoic acid)and its alkyl esters on virus growth and virion infectivity were examined. All the compounds tested showed an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1)in HEp-2 or Vero cells. The antiviral activity of gallic acid alkyl esters was enhanced by increasing the number of carbon in the alkyl moieties of the compounds, reaching maximum at a carbon number of 12 (lauryl gallate), but both cytocidal activity and cytopathic effect of the compounds were also significantly increased simultaneously. Among these compounds, octyl gallate showed a marked antiviral effect with a relatively moderate cytotoxity. In addition, octyl gallate suppressed the multiplication of RNA viruses, such as vesicular stomatitis virus and poliovirus. Quantitative characterization of the HSV-1 infection in the presence of octyl gallate revealed that: (1)this reagent can directly inactivate HSV-1 (virucidal activity), (2)it suppresses both the ntracellar multiplication and the release of the virus, (3)it selectively accelerates death of the virus-infected cells and (4)the addition of the reagent even at 6-h post infection completely abolishes the formation of progeny virus in the infected cells.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element OCTYL GALLATE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GALLIC ACID
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CELL DEATH
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HERPES SIMPLEX VIRUS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLIOVIRUS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Uozaki, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yamasaki, H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Katsuyama, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Higuchi, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Higuti, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Koyama, H.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1YLbMamWrIxkRx-vbHoq0d_A1GJEJJwui/view?usp=drivesdk">https://drive.google.com/file/d/1YLbMamWrIxkRx-vbHoq0d_A1GJEJJwui/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-10716 25.06.2025 25.06.2025 Documentos solicitados