Elastase-induced hvdrolvsis of synthetic solid subsrates: poly(ester-urea-urethane)and poly(ether-urea-urethane) (Record no. 45480)

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control field MX-MdCICY
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control field 20250625140647.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-11254
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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245 10 - TITLE STATEMENT
Title Elastase-induced hvdrolvsis of synthetic solid subsrates: poly(ester-urea-urethane)and poly(ether-urea-urethane)
490 0# - SERIES STATEMENT
Volume/sequential designation BioMaterials, 17, p.2381-2388, 1996
520 3# - SUMMARY, ETC.
Summary, etc. Human neutrophil elastase (HNE)and porcine pancreatic elastase (PPE)were incubated with two radiolabelled model poly(urethane)s, a poly(ester-urea-urethane)containing ['4C]toluene diisocyanate ([14C]TDl), poly(caprolactone)(PCL)and ethylenediamine (ED), and a poly(ether-urea-urethane)containing [14C]TDI, poly(tetramethylene oxide)(PTMO)and ED. Ten-fold more radioactive carbon was released when PPE was incubated with ['4C]TDI/PCLIED than when HNE was used. The PPE-induced radioactive carbon release was significantly reduced by a specific elastase inhibitor. Ten-fold less radioactive carbon was released when ['4C]TDI/PTMOIED was incubated with PPE as compared to ['4C]TDI/PCL/ED. Since neutrophils, which contain elastolytic activity, are present during the inflammatory response, the stability of biomaterials used in implanted devices may be affected.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLY(URETHANE)S
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BIODEGRADATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NEUTROPHIL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element INFLAMMATORY RESPONSE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HUMAN ELASTASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PORCINE ELASTASE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Labow, R.S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Erfle, D.J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Santerre, J.P.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1o8jRcW3UzhmfJzFsnUfpLJvBfA7arjas/view?usp=drivesdk">https://drive.google.com/file/d/1o8jRcW3UzhmfJzFsnUfpLJvBfA7arjas/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-11254 25.06.2025 25.06.2025 Documentos solicitados