Three Yeast Genes, PIRl, PIR2 and PIR3, Containing Internal Tandem Repeats, are Related to Each Other, and PIRI and PIR2 are Required for Tolerance to Heat Shock (Record no. 45554)

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control field MX-MdCICY
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control field 20250625140648.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-11332
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245 10 - TITLE STATEMENT
Title Three Yeast Genes, PIRl, PIR2 and PIR3, Containing Internal Tandem Repeats, are Related to Each Other, and PIRI and PIR2 are Required for Tolerance to Heat Shock
490 0# - SERIES STATEMENT
Volume/sequential designation Yeast, 9(5), p.481-494, 2004
520 3# - SUMMARY, ETC.
Summary, etc. We isolated three highly homologous genes, PIRl, PIR2 and PIR3, collectively called the PIR genes. The remarkable feature of their putative amino acid sequence is that they contain a sequence consisting of 18-19 amino acid residues repeated tandemly seven to ten times. Genes homologous to PIR were found in Kluyveromyces lactis and Zygosaccharomyces rouxii but not in Schizosaccharomycespombe, suggesting that a set of PIR genes plays some role in budding yeast. Bias of codon usage seen in each of the PZR translation products suggests that they are expressed abundantly. The fact that disruption of each gene is viable indicates that none of them is essential. The double disruptants, pirl pir2, were viable under various conditions, such as higher temperature (37°C)or high salt concentration, but showed a slow-growing phenotype on an agar slab. Furthermore, they were sensitive to heat shock. Addition of a pir3 disruption to the pirl pir2 double disruptant brought about no phenotypic difference from the original double mutant. PIRI and PIR3 are closely link ed to each other and are on chromosome XI.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GENE FAMILY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PROTEIN WITH INTERNAL REPEATS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element S. CEREVISIAE: HEAT SHOCK
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Akio Toh-E
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shuichi Yasunagat
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hideaki Nisogit
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kazuma Tanakas
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tomoko Oguchi
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yashushi Matsui
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1S36-egVjVadvbyDobLV3BWz7ssF6oAOb/view?usp=drivesdk">https://drive.google.com/file/d/1S36-egVjVadvbyDobLV3BWz7ssF6oAOb/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-11332 25.06.2025 25.06.2025 Documentos solicitados