Hydrolytic degradation of polyglyconate B: the relationship between degradation time,strength and molecular weight (Record no. 45639)

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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140650.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-11420
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Title Hydrolytic degradation of polyglyconate B: the relationship between degradation time,strength and molecular weight
490 0# - SERIES STATEMENT
Volume/sequential designation BioMaterials, 23(18), p.3905-3912, 2002
520 3# - SUMMARY, ETC.
Summary, etc. Bioresorbable polymers have found a wide range of uses in medical implants,from sutures to scaffolds for tissue engineering applications. Increasingly they are being used in internal orthopaedic fixation devices,in which the strength retention profile is important. Polyglyconate B,a block co-polymer of glycolic acid and trimethylene carbonate,is one polymer used in these applications. In this study,the hydrolytic degradation of polyglyconate B has been studied in vitro. Specimens were prepared with two initial molecular weights and aged in PBS solution at 371C for up to 31 days. The polymers were characterised by gel permeation chromatography,for molecular weight, tensile testing and mass change,as a function of degradation time. A further aim of the work was to determine whether the measured changes in tensile strength over time could be fitted to a simple model. The results showed that the observed relationship between strength and molecular weight was more complex than that used in our model. However, the data could be modelled using an empirically derived relationship between tensile strength and number average molecular weight ðMnÞ: Changes in other mechanical properties,such as strain at break,were also found to be strongly dependent on changes in the single parameter of Mn:
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYGLYCONATE B
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HYDROLYSIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BIODEGRADATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MECHANICAL PROPERTIES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MOLECULAR WEIGHT
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Farrar, D.F.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gillson, R.K.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Kb8MUXVbCQSafUwQ41qoHfXPAlRfWLPH/view?usp=drivesdk">https://drive.google.com/file/d/1Kb8MUXVbCQSafUwQ41qoHfXPAlRfWLPH/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-11420 25.06.2025 25.06.2025 Documentos solicitados