Further investigations on the hydrolytic degradation of poly (DL-lactide) (Record no. 45640)

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fixed length control field 01741nam a2200265Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140650.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-11421
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245 10 - TITLE STATEMENT
Title Further investigations on the hydrolytic degradation of poly (DL-lactide)
490 0# - SERIES STATEMENT
Volume/sequential designation BioMaterials, p.35-44, 1999
520 3# - SUMMARY, ETC.
Summary, etc. The hydrolytic degradation of poly(DL-lactide)(PLA50)material was investigated in order to elucidate the e¤ects of temperature and acidity of the external medium on the degradation characteristics. It was observed that at 60¡C and at pH"7.4, degradation was extremely rapid as compared with degradation at 37¡C. After only 2 days, heterogeneous degradation was observed due to larger internal autocatalysis. On the other hand, in the case of degradation at 37¡C in an acidic medium with pH"3.7, the heterogeneous degradation was preceeded by a much longer lag time. Water absorption was found to be pH dependent. At pH"7.4, water absorption was increased due to the osmotic pressure driving the bu¤er solution into the polymer matrix to neutralize acidic endgroups, which was not the case for degradation at pH"3.7. In both cases, the oligomeric stereocomplex was obtained as degradation residue at the end of the degradation period.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYLACTIDE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BIODEGRADABLE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HYDROLYSIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DEGRADATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CRYSTALLIZATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MORPHOLOGY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element STEREOCOMPLEX
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Li, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mccarthy, S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1a5EUQVJvFFt6iL_MNjd-Z8imTNqXg1El/view?usp=drivesdk">https://drive.google.com/file/d/1a5EUQVJvFFt6iL_MNjd-Z8imTNqXg1El/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-11421 25.06.2025 25.06.2025 Documentos solicitados