MARC details
| 000 -LEADER |
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| fixed length control field |
02673nam a2200337Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625140700.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-11967 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Quantitative analysis of total retronecine esters-type pyrrolizidine alkaloids in plant by high performance liquid chromatography |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
analytica chimica acta, 605(1), p.94-101, 2007 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Pyrrolizidine alkaloids (PAs)are alkaloids which typically contain a necine (7-hydroxy-1- hydroxymethyl-6,7-dihydro-5H-pyrrolizidine)base unit, and they can be found in one third of the higher plants around the world. They are hepatotoxic, mutagenic and carcinogenic and pose a threat to human health and safety. A specific, quick and sensitive method is therefore needed to detect and quantify the PAs sometimes in trace amount in herbs, tea or food products. Based on high performance liquid chromatography with prior derivatization of the alkaloids using o-chloranil and Ehrlich's reagent, we report an improved method for quantitative analysis of the total amount of retronecine esters-type pyrrolizidine alkaloids (RET-PAs)in a plant extract. The total quantitation of RET-PAs is achieved because of a common colored retronecine marker, a 7-ethoxy-1-ethoxylmethyl retronecine derivative, is produced with all the different RET-PAs during the derivatization reaction. The chemical identity of the common retronecine marker was characterized on-line by positive mode electrospray ionization mass spectrometry and nuclear magnetic resonance spectroscopy. The limit of detection using the improved method is 0.26 nmolmL-1 and the limit of quantitation is 0.79 nmolmL-1. The advantages of this method are much enhanced sensitivity in detection and quantitation, and, no restriction on the choice of RET-PA as a calibration standard. Application of the developed method to the quantitation of total RET esters-type PAs in Senecio scandens from different regions of China is also reported. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
RETRONECINE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PYRROLIZIDINE ALKALOIDS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
DIMETHYLAMINOBENZALDEHYDE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
HIGH PERFORMANCE LIQUID |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CHROMATOGRAPHY-MASS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SPECTROMETRY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SENECIO SCANDENS |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhang, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wang, C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Xiong, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wang, W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Yang, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Branford-White, C.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wang, Z. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wang, Z. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1xZXEDpbIeAv6rSuQMQ6_Y7r5Kvn9C76d/view?usp=drivesdk">https://drive.google.com/file/d/1xZXEDpbIeAv6rSuQMQ6_Y7r5Kvn9C76d/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
