Manufacture of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate)hydrogel tubes for use as nerve guidance channels (Record no. 46302)

MARC details
000 -LEADER
fixed length control field 02283nam a2200277Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140703.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12091
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Manufacture of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate)hydrogel tubes for use as nerve guidance channels
490 0# - SERIES STATEMENT
Volume/sequential designation BioMaterials, 23(18), p.3843-3851, 2002
520 3# - SUMMARY, ETC.
Summary, etc. Hydrogel tubes of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate)(p(HEMA-co-MMA)) made by liquid-liquid centrifugal casting are being investigated as potential nerve guidance channels in the central nervous system. An important criterion for the nerve guidance channel is that its mechanical properties are similar to those of the spinal cord, where it will be implanted. The formulated p(HEMA-co-MMA)tubes are soft and flexible, consistingof a gel-like outer layer, and an interconnected macroporous, inner layer. The relative thickness of the gel phase to macroporous phase is controlled by the formulation chemistry, and specifically by the ratio of co-monomers, HEMA and MMA. By varyingthe surface chemistry of the mold within which the tubes are synthesized, tubes were prepared with either a ''cracked'' or a smooth outer morphology. Tubes with the cracked outer morphology had periodic channels that traversed the wall of the tube, which resulted in a lower modulus than smooth outer morphology tubes, yet likely greater diffusive permeability. For tubes (and not rods)to be formed, phase separation must precede gelation as is detailed in a formulation phase diagram for HEMA, MMA and water. The tensile elastic modulus of p(HEMA-co-MMA)tubes reflected the formulation chemistry, with greater moduli (up to 400 kPa)recorded for tubes having 10wt
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element 2-HYDROXYETHYL METHACRYLATE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHASE SEPARATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TUBES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LIQUID-LIQUID CENTRIFUGAL CASTING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NERVE REGENERATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHEMA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HEMA
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Dalton, P.D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Flynn, L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shoichet, M.S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1YSm7vWhSaKhV9sid4U774DX43vB52-vR/view?usp=drivesdk">https://drive.google.com/file/d/1YSm7vWhSaKhV9sid4U774DX43vB52-vR/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12091 25.06.2025 25.06.2025 Documentos solicitados