Adenylate cyclase activity of TIR1/AFB auxin receptors in plants (Record no. 46325)
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| fixed length control field | 01855nam a2200241Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140703.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-21114 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Adenylate cyclase activity of TIR1/AFB auxin receptors in plants |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Nature, 611(7934), p.133-138, 2022 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | The phytohormone auxin is the major coordinative signal in plant development1, mediating transcriptional reprogramming by a well-established canonical signalling pathway. TRANSPORT INHIBITOR RESPONSE 1 (TIR1)/AUXIN-SIGNALING F-BOX (AFB)auxin receptors are F-box subunits of ubiquitin ligase complexes. In response to auxin, they associate with Aux/IAA transcriptional repressors and target them for degradation via ubiquitination2,3. Here we identify adenylate cyclase (AC)activity as an additional function of TIR1/AFB receptors across land plants. Auxin, together with Aux/IAAs, stimulates cAMP production. Three separate mutations in the AC motif of the TIR1 C-terminal region, all of which abolish the AC activity, each render TIR1 ineffective in mediating gravitropism and sustained auxin-induced root growth inhibition, and also affect auxin-induced transcriptional regulation. These results highlight the importance of TIR1/AFB AC activity in canonical auxin signalling. They also identify a unique phytohormone receptor cassette combining F-box and AC motifs, and the role of cAMP as a second messenger in plants. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Qi, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kwiatkowski, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hoermayer, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sinclair, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zou, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Friml, J. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/open?id=12rgOxxeV8pjHv6iVBgfTN7BFaKgK2I5F&usp=drive_copy">https://drive.google.com/open?id=12rgOxxeV8pjHv6iVBgfTN7BFaKgK2I5F&usp=drive_copy</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-21114 | 25.06.2025 | 25.06.2025 | Documentos solicitados |