Hypoglycemic effects of sesquiterpene lactones from Byrsonima crassifolia (Record no. 46333)

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fixed length control field 01729nam a2200229Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140703.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21122
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245 10 - TITLE STATEMENT
Title Hypoglycemic effects of sesquiterpene lactones from Byrsonima crassifolia
490 0# - SERIES STATEMENT
Volume/sequential designation Food Science and Biotechnology, 25, p.1135-1145, 2016
520 3# - SUMMARY, ETC.
Summary, etc. The novel dimeric guaianolides sesquiterpene lactone Byrsoninas A and B from seed hexane extract of Byrsonima crassifolia were identified. Streptozotocin-induced mildly diabetic and severely diabetic mice were treated with these oral administrations at a dosage of 20 mg/kg of body weight per day for 30 days. Also the protective effect in vitro in RIN-5F cells against oxidative stress was investigated and TNF-? and IL-6 levels were measured. Both Byrsonina types reduced blood glucose, cholesterol, triglyceride, lipoprotein, and transaminase levels and increased HDL-cholesterol, antioxidant enzymes, and TBARS-reactive substance levels. Byrsoninas A and B both improved this glucose metabolism by reducing insulin resistance and by stimulating insulin production due to protection effect for pancreatic ?-cells against oxidative stress, lipid abnormalities were reduced and, chronic inflammation responses were alleviated producing a hepatoprotective role.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GUAIANOLIDES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIDIABETIC
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HYPERLIPIDEMIA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BYRSONIMA CRASSIFOLIA
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gutiérrez, R. M. P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ramirez, A. M.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/open?id=1hxvRSm9ZpMYC7CO_cgkFDXjWu-EQ3dZL&usp=drive_copy">https://drive.google.com/open?id=1hxvRSm9ZpMYC7CO_cgkFDXjWu-EQ3dZL&usp=drive_copy</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-21122 25.06.2025 25.06.2025 Documentos solicitados