Plant virus-mediated induction of miR168 is associated with repression of ARGONAUTE1 accumulation (Record no. 46451)
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| 000 -LEADER | |
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| fixed length control field | 01969nam a2200265Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140705.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-12240 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Plant virus-mediated induction of miR168 is associated with repression of ARGONAUTE1 accumulation |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | The EMBO Journal, 29(20), p.3507-3519, 2010 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Virus infections induce the expression of ARGONAUTE1 (AGO1)mRNA and in parallel enhance the accumulation of miR168 (regulator of AGO1 mRNA). Here, we show that in virus-infected plants the enhanced expression of AGO1 mRNA is not accompanied by increased AGO1 protein accumulation. We also show that the induction of AGO1 mRNA level is a part of the host defence reaction, whereas the induction of miR168, which overlaps spatially with virus-occupied sectors, is mediated mainly by the Tombusvirus p19 RNA-silencing suppressor. The absence of p19 results in the elimination of miR168 induction and accompanied with the enhanced accumulation of AGO1 protein. In transient expression study, p19 mediates the induction of miR168 and the down-regulation of endogenous AGO1 level. P19 is not able to efficiently bind miR168 in virus-infected plants, indicating that this activity is uncoupled from the small RNA-binding capacity of p19. Our results imply that plant viruses can inhibit the translational capacity of AGO1 mRNA by modulating the endogenous miR168 level to alleviate the anti-viral function of AGO1 protein. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HOST DEFENCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MIR168 |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PLANT VIRUS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA-SILENCING SUPPRESSOR |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Várallyay, E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Válóczi, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ágyi, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Burgyán, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Havelda, Z. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1E8C3tASX7BSiqGt6qjWt5SNlIuP9yaUi/view?usp=drivesdk">https://drive.google.com/file/d/1E8C3tASX7BSiqGt6qjWt5SNlIuP9yaUi/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-12240 | 25.06.2025 | 25.06.2025 | Documentos solicitados |