The impact of next-generation sequencing technology on genetics (Record no. 46496)

MARC details
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control field MX-MdCICY
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control field 20250625153850.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12286
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Title The impact of next-generation sequencing technology on genetics
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Volume/sequential designation Trends in Genetics, 24(3), p.133-141, 2008
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Summary, etc. If one accepts that the fundamental pursuit of genetics is to determine the genotypes that explain phenotypes, the meteoric increase of DNA sequence information applied toward that pursuit has nowhere to go but up. The recent introduction of instruments capable of producing millions of DNA sequence reads in a single run is rapidly changing the landscape of genetics, providing the ability to answer questions with heretofore unimaginable speed. These technologies will provide an inexpensive, genome-wide sequence readout as an endpoint to applications ranging from chromatin immunoprecipitation, mutation mapping and polymorphism discovery to noncoding RNA discovery. Here I survey next-generation sequencing technologies and consider how they can provide a more complete picture of how the genome shapes the organism.
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Personal name Mardis, E.R.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1AiPLqfM1P7kNZzKM0e54L4WAnqQW7qEi/view?usp=drivesdk">https://drive.google.com/file/d/1AiPLqfM1P7kNZzKM0e54L4WAnqQW7qEi/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12286 25.06.2025 25.06.2025 Documentos solicitados