Antimicrobial Activity of Juglone (Record no. 46553)

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003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153851.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12344
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245 10 - TITLE STATEMENT
Title Antimicrobial Activity of Juglone
490 0# - SERIES STATEMENT
Volume/sequential designation Phytotherapy Research, 4(1), p.11-14, 1990
520 3# - SUMMARY, ETC.
Summary, etc. The juice of freshly macerated unripe hulls of the black walnut (Jugluns nigru)has been used for many years in folk medicine as a treatment for localized, topical fungal infections such as ringworm. It has been proposed that the biological activity of the walnut hulls is due to the presence of the simple naphthoquinone, juglone 5-hydroxy-1,4-naphthoquinone), which has been isolated from the unripe hulls by sublimation. Since the fresh juice of unripe walnut hulls is utilized for the treatment of ringworm, and since it has been speculated that the activity is due to the presence of juglone, it was of interest to determine the efficacy of juglone as compared to standard commercially available antifungal agents. The comparative efficacy was determined by evaluation of the minimum inhibitory concentration (MIC)values of juglone and the standard antifungal agents clotrimazole, triacetin, tolnaftate, griseofulvin, zinc undecylenate, selenium sulfide as well as two investigational antifungal ntibiotics, liriodenine and liriodenine methiodide, for two dermatophytes, Trichophyton mentagrophytes and Microsporum gypseum. MIC values for juglone showed it to have moderate antifungal activity and to be as effective as certain commercially available antifungal agents such as zinc undecylenate and selenium sulfide.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element JUGLONE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element JUGLUNS NIGRU
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ATHLETE'S FOOT
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIMICROBIAL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIFUNGAL
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Clark, A.M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jurgens, T.M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hufford, C.D.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1zQimD0DTfaW8UKHSbM69TeRQ89E1e2QM/view?usp=drivesdk">https://drive.google.com/file/d/1zQimD0DTfaW8UKHSbM69TeRQ89E1e2QM/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12344 25.06.2025 25.06.2025 Documentos solicitados