Naphthoquinone spiroketal with allelochemical activity from the newly discovered endophytic fungus Edenia gomezpompae (Record no. 46580)

MARC details
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153852.0
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Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12372
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245 10 - TITLE STATEMENT
Title Naphthoquinone spiroketal with allelochemical activity from the newly discovered endophytic fungus Edenia gomezpompae
490 0# - SERIES STATEMENT
Volume/sequential designation PhytoChemistry, 69(5), p.1185-1196, 2008
520 3# - SUMMARY, ETC.
Summary, etc. Chemical investigation of the mycelium of Edenia gomezpompae, a newly discovered endophytic fungus isolated from the leaves of Callicarpa acuminata (Verbenaceae)collected from the ecological reserve El Eden, Quintana Roo, Mexico, resulted in the isolation of four naphthoquinone spiroketals, including three new compounds and palmarumycin CP2 (4). We elucidated the structures of the metabolites by extensive NMR spectroscopy studies, including DEPT, COSY, NOESY, HSQC, HMBC, and chiroptical methods. The trivial names proposed for these compounds are preussomerin EG1 (1), preussomerin EG2 (2)and preussomerin EG3 (3). In addition, the X-ray data for 4 were obtained. The bioactivity of the mycelial organic extracts and the pure compounds was tested against three endophytic fungi (Colletotrichum sp., Phomopsis sp., and Guignardia manguifera)isolated from the same plant species (C. acuminata, Verbenaceae)and against four economically important phytopathogenic microorganisms (two fungoid oomycetes, Phythophtora capsici and Phythophtora parasitica, and the fungi Fusarium oxysporum and Alternaria solani). Spiroketals 1-3 displayed significant growth inhibition against all the phytopathogens. IC50 values for the four phytopathogens were from 20 to 170 lg/ml. Palmarumycin CP2 (4)was not bioactive against any of the fungi tested. Compound 1 showed the strongest bioactivity. The acetylated derivatives of preussomerin EG1 (1), 1a and 1b, were obtained and their biological activity was tested on endophytes and phytopathogens. Preussomerin EG1 1, 1a and 1b exhibited significant bioactivity against all microorganisms tested with the exception of Alternaria solani. This is the first report of allelochemicals with antifungal activity from the newly discovered endophytic fungus E. gomezpompae.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element EDENIA GOMEZPOMPAE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ENDOPHYTIC FUNGI
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Topical term or geographic name entry element CALLICARPA ACUMINATA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element VERBENACEAE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ALLELOCHEMICALS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NAPHTHOQUINONE SPIROKETALS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PREUSSOMERIN EG1
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Topical term or geographic name entry element PREUSSOMERIN EG2
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Topical term or geographic name entry element PREUSSOMERIN EG3
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PALMARUMYCIN CP2
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHYTOPATHOGENIC FUNGI
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHYTOPATHOGENIC FUNGOID OOMYCETES
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Macías-Rubalcava, M.L.
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Personal name Hernández-Bautista, B.E.
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Personal name Jiménez-Estrada, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name González, M.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Glenn, A.E.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hanlin, R.T.
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Personal name Hernández-Ortega, S.
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Personal name Hernández-Ortega, S.
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Personal name Muria-González, J.M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Anaya, A.L.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1YIS-N5-vbqZzivQp2q19Q7cMfH1o376L/view?usp=drivesdk">https://drive.google.com/file/d/1YIS-N5-vbqZzivQp2q19Q7cMfH1o376L/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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