Viral Vectors for Production of Recombinant Proteins in Plants (Record no. 46699)

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fixed length control field 02278nam a2200193Ia 4500
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153855.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12492
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245 10 - TITLE STATEMENT
Title Viral Vectors for Production of Recombinant Proteins in Plants
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Volume/sequential designation Journal of Cell. Physiol, 216(2), p.366-377, 2008
520 3# - SUMMARY, ETC.
Summary, etc. Global demand for recombinant proteins has steadily accelerated for the last 20 years. These recombinant proteins have a wide range of important applications, including vaccines and therapeutics for human and animal health, industrial enzymes, new materials and components of novel nano-particles for various applications. The majority of recombinant proteins are produced by traditional biological ''factories,'' that is, predominantly mammalian and microbial cell cultures along with yeast and insect cells. However, these traditional technologies cannot satisfy the increasing market demand due to prohibitive capital investment requirements. During the last two decades, plants have been under intensive investigation to provide an alternative system for cost-effective, highly scalable, and safe production of recombinant proteins. Although the genetic engineering of plant viral vectors for heterologous gene expression can be dated back to the early 1980s, recent understanding of plant virology and technical progress in molecular biology have allowed for significant improvements and fine tuning of these vectors. These breakthroughs enable the flourishing of a variety of new viral-based expression systems and their wide application by academic and industry groups. In this review, we describe the principal plant viral-based production strategies and the latest plant viral expression systems, with a particular focus on the variety of proteins produced and their applications. We will summarize the recent progress in the downstream processing of plant materials for efficient extraction and purification of recombinant proteins.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lico, C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chen, Q.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Santi, L.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/13KvXxY00tqSTgL972Uow0dLKELv8Ript/view?usp=drivesdk">https://drive.google.com/file/d/13KvXxY00tqSTgL972Uow0dLKELv8Ript/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12492 25.06.2025 25.06.2025 Documentos solicitados