Structure-Activity Relationship in the Interaction of Substituted Perinaphthenones with Mycosphaerella fijiensis (Record no. 47045)

MARC details
000 -LEADER
fixed length control field 02150nam a2200325Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153910.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12840
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245 10 - TITLE STATEMENT
Title Structure-Activity Relationship in the Interaction of Substituted Perinaphthenones with Mycosphaerella fijiensis
490 0# - SERIES STATEMENT
Volume/sequential designation J. Agric. Food Chem., 57, p.7417-7421, 2009
520 3# - SUMMARY, ETC.
Summary, etc. The levels of native fungitoxic perinaphthenone phytoalexins in susceptible Musa varieties (banana), which are commercially grown in large plantations, are too low to provide plants with long-lasting protection against highly pathogenic fungi. Novel strategies for plant protection are necessary to reduce crop losses and to prevent the development of resistant fungal strains. The synthesis of novel fungicides based on the structures of perinaphthenone natural products is considered to be a promising strategy. Thirteen substituted perinaphthenones, among them two known natural products (1, 2)and 11 synthetics (3-13), were evaluated for their activity against Mycosphaerella fijiensis, and their half-maximal inhibitory concentrations (IC50)were calculated to establish structure-activity relationships (SAR). A SAR trend was hypothesized, leading to the design of a new compound, 4-methoxy-2-nitro-1H-phenalen-1-one (14); the new compound displayed significantly enhanced in vitro activity against M. fijiensis compared to other perinaphthenone derivatives. The activity of 14 was comparable to that of two commercial fungicides.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MYCOSPHAERELLA FIJIENSIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BANANA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PERINAPHTHENONE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHENALENONE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHOTOTOXICITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element REACTIVE OXYGEN SPECIES
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hidalgo, W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Duque, L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Saez, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Arango, R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gil, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rojano, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Schneider, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Schneider, B.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1DawuEk80iVjxzsrI0hvkPP4dRhq0UPbm/view?usp=drivesdk">https://drive.google.com/file/d/1DawuEk80iVjxzsrI0hvkPP4dRhq0UPbm/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12840 25.06.2025 25.06.2025 Documentos solicitados