Histone demethylases in chromatin cross-talks (Record no. 47122)

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control field MX-MdCICY
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control field 20250625153912.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12920
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Title Histone demethylases in chromatin cross-talks
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Volume/sequential designation Biology of the Cell, 103, p.381-401, 2011
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Summary, etc. The 'histone code' hypothesis states that chromatin-based regulation of nuclear processes such as transcription is brought about by the combination of distinct modifications (histone marks)at specific loci. Its correct establishment involves chromatin cross-talks, ensuring an ordered and concerted deposition/removal of a particular set of modifications that act together to give the correct transcriptional outcome. Histone methylation on lysine residues can negatively or positively impact on gene transcription, depending on the residue and on its degree of methylation. Thanks to this complexity and given the number of chromatin 'readers' that can recognize methylated lysine residues, histone methylation plays a very special role in specifying the various chromatin states. The recent discovery of histone demethylases, which represent a large family of enzymes often containing histone modification binding modules, sheds new light on cross-talk mechanisms involving methylated residues. In the present review, after a brief overview of the various families of histone demethylases, we describe the different mechanisms by which they participate in chromatin cross-talks and how these mechanisms are integrated to achieve the mutual exclusion or the link between chromatin marks, leading to the establishment of the correct histone code.
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Personal name Verrier, L.
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Personal name Vandromme, M.
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Personal name Trouche, D.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/114p4WJL3nWGRoXMEowLrAhrl4iKKF1iw/view?usp=drivesdk">https://drive.google.com/file/d/114p4WJL3nWGRoXMEowLrAhrl4iKKF1iw/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12920 25.06.2025 25.06.2025 Documentos solicitados