MARC details
| 000 -LEADER |
| fixed length control field |
03308nam a2200361Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
| control field |
20250625153913.0 |
| 040 ## - CATALOGING SOURCE |
| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-12974 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
| Title |
Pancreatic Intraepithelial Neoplasia A New Nomenclature and Classification System for Pancreatic Duct Lesions |
| 490 0# - SERIES STATEMENT |
| Volume/sequential designation |
The American Journal of Surgical Pathology, 25(5), p.579-586, 2008 |
| 520 3# - SUMMARY, ETC. |
| Summary, etc. |
Proliferative epithelial lesions in the smaller caliber pancreatic ducts and ductules have been the subject of numerous morphologic, clinical, and genetic studies; however, a standard nomenclature and diagnostic criteria for classifying these lesion have not been established. To evaluate the uniformity of existing systems for grading duct lesions in the pancreas, 35 microscopic slides with 35 representative duct lesions were sent to eight expert pathologists from the United States, Canada, and Europe. Kappa values for interobserver agreement could not be calculated initially because more than 70 different diagnostic terms were used by the eight pathologists. In several cases, the diagnoses rendered for a single duct lesion ranged from "hyperplasia," to "metaplasia," to "dysplasia," to "carcinoma in situ." This review therefore demonstrated the need for a standard nomenclature and classification system. Subsequently, during a working group meeting, the pathologists agreed to adopt a single standard system. The terminology pancreatic intraepithelial neoplasia (or PanIN)was elected, and diagnostic criteria for each grade of PanIN were established (http://pathology.jhu.edu/pancreas_panin). This new system was then evaluated by having the eight pathologists rereview the original 35 cases. Only seven different diagnoses were rendered, and kappa values of 0.43, 0.14, and 0.42 were obtained for PanINs 1, 2, and 3 respectively. Cases assigned other diagnoses (e.g., squamous metaplasia)collectively had a kappa value of 0.41. These results show both the potential of the classification system, and also the difficulty of classifying these lesions even with a consistent nomenclature. However, even when there is lack of consensus, having a restricted set of descriptions and terms allows a better understanding of the reasons for disagreement. It is suggested that we adopt and apply this system uniformly, with continued study of its reliability and use, and possibly further refinement. The acceptance of a standard classification system will facilitate the study of pancreatic duct lesions, and will lead ultimately to a better understanding of their biologic importance. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
PANCREAS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
PANCREATIC |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
NEOPLASIA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
CARCINOMA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
IN SITU. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Hruban, R.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Volkan Adsay, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Albores-Saavedra, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Compton, C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Garrett, E.S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Goodman, S.N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Kern, S.E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Kern, S.E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Klöppel, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Longnecker, D.S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Lüttges, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Offerhaus, G.J.A. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1ciXagkw4Gd4cCoMvIRbZkv61R7qt9_ao/view?usp=drivesdk">https://drive.google.com/file/d/1ciXagkw4Gd4cCoMvIRbZkv61R7qt9_ao/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |