Chemical Genetics Reveals Negative Regulation of Abscisic Acid Signaling by a Plant Immune Response Pathway (Record no. 47206)
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| fixed length control field | 02496nam a2200325Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625153914.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-13004 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Chemical Genetics Reveals Negative Regulation of Abscisic Acid Signaling by a Plant Immune Response Pathway |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Current Biology, 21(7), p.990-997, 2011 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Coordinated regulation of protection mechanisms against environmental abiotic stress and pathogen attack is essential for plant adaptationandsurvival. Initial abioticstresscaninterfere with disease-resistancesignaling[1-6].Conversely, initial plant immune signaling may interrupt subsequent abscisic acid (ABA)signal transduction [7, 8]. However, the processes involved in this crosstalk between these signaling networks have not been determined. By screening a 9600-compound chemical library,weidentifiedasmallmolecule [5-(3,4-dichlorophenyl)furan-2-yl]-piperidine-1-ylmethanethione (DFPM)that rapidly downregulates ABA-dependent gene expression and also inhibits ABA-induced stomatal closure. Transcriptome analyses show that DFPM also stimulates expression of plant defense-related genes.Major early regulators of pathogen- resistanceresponses, includingEDS1,PAD4,RAR1,and SGT1b, are required for DFPM-and notably also for Pseudomonas- interference with ABA signal ansduction, whereas salicylic acid, EDS16, and NPR1 are not necessary. Although DFPM does not interfere with early ABA perception by PYR/RCAR receptors or ABA activation of SnRK2 kinases, it disrupts cytosolic Ca2+ signaling and downstream anion channel activation in a PAD4-dependentmanner. Our findings provide evidence that activation of EDS1/PAD4-dependent plant immune responses rapidly disrupts ABA signal transduction and that this occurs at the level of Ca2+ signaling, illuminating how the initial biotic stress pathway interferes with ABA signaling. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hauser, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ha, T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xue, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bohmer, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nishimura, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Munemasa, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Munemasa, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Peine, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Robert, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Parker, J.E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schroede, J.I. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1xw2ugkejx7CjSF-ENGpROgav93i2N6Pn/view?usp=drivesdk">https://drive.google.com/file/d/1xw2ugkejx7CjSF-ENGpROgav93i2N6Pn/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-13004 | 25.06.2025 | 25.06.2025 | Documentos solicitados |