Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF (Record no. 47320)

MARC details
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fixed length control field 01981nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153916.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-13118
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245 10 - TITLE STATEMENT
Title Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF
490 0# - SERIES STATEMENT
Volume/sequential designation Journal of Controlled Release, 143(2), p.168-174, 2010
520 3# - SUMMARY, ETC.
Summary, etc. Artificial nerve conduits (NC)can clinically be instrumental for facilitating the surgery of damaged peripheral nerves. To improve axonal regeneration of injured peripheral nerves, we have developed collagen nerve conduits (NC)releasing glial cell line-derived neurotrophic factor (GDNF)alone or in combination with nerve growth factor (NGF), which exert synergistic action on axonal growth. Degradation of the NC and their mechanical and drug release properties were controlled by two means: (i)cross-linking the collagen tubes by physical means, through a dehydro-thermal treatment (DHT), before loading with the neurotrophic factors (NTFs)GDNF or GDNF/NGF; and (ii)coating the drug-loaded collagen tubes with layers of poly (lactide-co-glycolide)(PLGA). Non-cross-linked collagen NC (C-NC)released high amounts of NTFs during the initial 2.3 days of incubation, whereas the DHT-treated collagen NC (Cdht-NC)did not show a prominent burst effect. The release kinetics was similar for DNF alone and GDNF co-delivered with NGF. Within 30 days, the C-NC released 78
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GROWTH FACTORS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CONTROLLED CO-DELIVERY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NERVE CONDUITS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element COLLAGEN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MECHANICAL STABILITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DORSAL ROOT GANGLIA
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Madduri, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Feldman, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tervoort, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Papaloïzos, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gander, B.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1x4J2m4wbpZFvWrMXLtjrR9taMjyVwCNK/view?usp=drivesdk">https://drive.google.com/file/d/1x4J2m4wbpZFvWrMXLtjrR9taMjyVwCNK/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-13118 25.06.2025 25.06.2025 Documentos solicitados