MARC details
| 000 -LEADER |
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| fixed length control field |
02753nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625153918.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-13192 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Bactericidal effect of silver nanoparticles against multidrug-resistant bacteria |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
World J Microbiol Biotechnol, 26(4), p.615-621, 2010 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Infections caused by drug-resistant microorganisms result in significant increases in mortality, morbidity, and cost related to prolonged treatments. The antibacterial activity of silver nanoparticles against some drug-resistant bacteria has been established, but further investigation is needed to determine whether these particles could be an option for the treatment and prevention of drugresistant microbial infections. Hence, we challenged ifferent drug-resistant pathogens of clinical importance (multidrug-resistant Pseudomonas aeruginosa, ampicillinresistant Escherichia coli O157:H7 and erythromycinresistant Streptococcus pyogenes)with a suspension of silver nanoparticles. By means of a luciferase-based assay, it was determined that silver nanoparticles (1)inactivate a panel of drug-resistant and drug-susceptible bacteria (Gram positive and Gram negative), (2)exert their antibacterial activity through a bactericidal rather than bacteriostatic mechanism, and (3)inhibit the bacterial growth rate from the time of first contact between the bacteria and the nanoparticles. Additionally, strains with a resistant phenotype to silver nanoparticle were developed and used to explore the bactericidal mode of action of silver nanoparticles. Through a Kirby-Bauer test, it was shown that silver nanoparticles' general mechanism of bactericidal action is based on inhibition of cell wall synthesis, protein synthesis mediated by the 30s ribosomal subunit, and nucleic acid synthesis. Our data suggest that silver nanoparticles are effective broadspectrum biocides against a variety of drug-resistant bacteria, which makes them a potential candidate for use in pharmaceutical products and medical devices that may help to prevent the transmission of drug-resistant pathogens in different clinical environments. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
DRUG-RESISTANT BACTERIA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SILVER NANOPARTICLES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SILVER RESISTANCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BROAD-SPECTRUM AGENT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BACTERICIDAL AGENT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
NANOBIOTECHNOLOGY |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lara, H.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ayala-Nuñez, N.V. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ixtepan Turrent, L.C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Rodríguez Padilla, C. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1JCE7x6vRWnJQQ-uKbHTTJH0hwRsa9Sf_/view?usp=drivesdk">https://drive.google.com/file/d/1JCE7x6vRWnJQQ-uKbHTTJH0hwRsa9Sf_/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
