Scale-up of a pharmaceutical granulation in fixed bowl mixer-granulators (Record no. 47653)

MARC details
000 -LEADER
fixed length control field 01590nam a2200253Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153923.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-13453
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Scale-up of a pharmaceutical granulation in fixed bowl mixer-granulators
490 0# - SERIES STATEMENT
Volume/sequential designation International Journal of Pharmaceutics, 133(1-2), p.127-131, 1996
520 3# - SUMMARY, ETC.
Summary, etc. Scale-up in fixed bowl mixer-granulators has been studied by applying the classical dimensionless numbers of Power, Reynolds and Froude to end-point prediction in a range of geometrically similar machines. The simple relationship of Power number/Reynolds number, as suggested by previous workers, has been found to be nappropriate for large-scale production machines where corrections have to be made for gross vortexing and powder bed height variation by the incorporation of the Froude number and a scaling factor. When corrections are made, data from 25-, 100- and 600-1 machines all fall on the same curve allowing predictions of optimum granulation end-point conditions to be made for production-scale equipment from measurements on laboratory-scale equipment and vice-versa.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GRANULATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MIXER GRANULATORS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SCALE-UP
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Landin, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name York, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cliff, M.J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rowe, R.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wigmore, A.J.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1vvguDzaJTI19g8n1JPJrhEwPVrF3zQIf/view?usp=drivesdk">https://drive.google.com/file/d/1vvguDzaJTI19g8n1JPJrhEwPVrF3zQIf/view?usp=drivesdk</a>
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-13453 25.06.2025 25.06.2025 Documentos solicitados