Leishmaniasis: focus on the design of nanoparticulate vaccine delivery systems (Record no. 47710)

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fixed length control field 01969nam a2200253Ia 4500
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153924.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-13511
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245 10 - TITLE STATEMENT
Title Leishmaniasis: focus on the design of nanoparticulate vaccine delivery systems
490 0# - SERIES STATEMENT
Volume/sequential designation Expert Rev. Vaccines, 11(1), p.69-86, 2012
520 3# - SUMMARY, ETC.
Summary, etc. Although mass vaccination of the entire population of an endemic area would be the most cost-effective tool to diminish Leishmania burden, an effective vaccine is not yet commercially available. Practically, vaccines have failed to achieve the required level of protection, possibly owing to the lack of an appropriate adjuvant and/or delivery system. Therefore, there is still an imperative demand for an improved, safe and efficient delivery system to enhance the immunogenicity of available vaccine candidates. Nanoparticles are proficient in boosting the quality and magnitude of immune responses in a predictable fashion. Herein, we discuss how nanoparticulate vaccine delivery systems can be used to induce appropriate immune responses against leishmaniasis by controlling physicochemical properties of the vaccine. Stability, production reproducibility, low cost per dose and low risk-benefit ratios are desirable characteristics of an ideal vaccine formulation and solid lipid nanoparticles may serve as one of the most promising practical strategies to help to achieve such a leishmanial vaccine, at least in canine species in the developing world.
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Topical term or geographic name entry element ADJUVANT
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Topical term or geographic name entry element DELIVERY SYSTEM
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LEISHMANIASI
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NANOPARTICLE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SOLID LIPID NANOPARTICLE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element VACCINATION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Delaram Doroud
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sima Rafati
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1v2FvoTybDkbWwudbbk4hJj5V_YvrQVF3/view?usp=drivesdk">https://drive.google.com/file/d/1v2FvoTybDkbWwudbbk4hJj5V_YvrQVF3/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-13511 25.06.2025 25.06.2025 Documentos solicitados