MARC details
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03780nam a2200373Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625153930.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-13834 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Chemical fingerprinting and bioactivity of Amazonian Ecuador Croton lechleri Müll. Arg. (Euphorbiaceae)stem bark essential oil: A new functional food ingredient? |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Food Chemistry, 126(3), p.837-848, 2011 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Croton lechleri essential oil has been obtained by steam distillation of fresh stem bark from Amazonian Ecuador adult plants (yield: 0.61 ml/kg [0.061 percent]; density: 1.01 g/ml), and then chemically characterised by GC (Gas Chromatography)and GC-MS (gas chromatography-mass spectrometry). Seventy-four chemicals were detected and identified; the most abundant in descending order, were the sesquiterpenes sesquicineole (17.29 percent), ?-calacorene (11.29 percent), 1,10-di-epi-cubenol (4.75 percent), ?-calacorene (4.34 percent)and epi-cedrol (4.09 percent). Monoterpenes checked with a relative peak area higher than 2.0 percent were ?-pinene (2.01 percent), p-cymene (2.61 percent), limonene (4.20 percent)and borneol (2.67 percent). The structure of the main chemicals were confirmed by GC-MS and 1H NMR analyses. Spectrophotometric 1,1-diphenyl-2-picrylhydrazyl (DPPH)and DPPH-(high performance)thin layer chromatography (DPPH-(HP)TLC)bioautographic assays showed a lower radical scavenging capacity (IC50)with respect to commercial thyme essential oil and BHA (butylated hydroxyl anisole), pointing out, however, that the C. lechleri essential oil fraction, characterised by ?-calacorene, ?-calacorene and ?-cadalene, was the most involved in the bioactivity. Similar results were obtained with ?-carotene bleaching assay, where the IC50 values were 0.291 ± 0.024 mg/ml for C. lechleri essential oil, 0.164 ± 0.013 and 1.34 × 10?4 ± 10?5 mg/ml for thyme essential oil and BHA, respectively. (HP)TLC-bioautographic assay performed with Gram positive and Gram negative bacteria revealed a minimum inhibitory concentration (MIC)values comprised between 0.10 mg/ml (Escherichia coli)and 10.10 mg/ml (for e.g. Pseudomonas aeruginosa), and the fraction mainly characterised by sesquicineole (97.38 percent)as the most involved in antibacterial capacity. Ames test employing Salmonella typhimurium TA98 and TA100 with and without a metabolic activation mixture (S9 mix)demonstrated the absence of mutagenicity of the C. lechleri essential oil between a concentration range of 10?2 and 100 mg/plate. The same results were achieved by Saccharomyces cerevisiae D7 strain assay. An interesting mutagen-protective efficacy was evidenced by a 30 percent and 33 percent revertants reduction of TA98 strain treated with 2-aminoanthracene and nitrofluorene (2 ?g/plate), suggesting, above all, the possibility to employ C. lechleri essential oil as a new flavouring protective ingredient for foods or dietary supplements against potential mutagens formed during cooking and/or processing in general. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CROTON LECHLERI |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ESSENTIAL OIL |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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GC |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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GC-MS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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NMR |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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ANTIOXIDANT ACTIVITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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ANTIMICROBIAL ACTIVITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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(HP)TLC-BIOAUTOGRAPHY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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CYTOTOXICITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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MUTAGENIC ACTIVITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTI-MUTAGENIC ACTIVITY |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Rossi, D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Guerrini, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Maietti, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Bruni, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Paganetto, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Poli, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Sacchetti, G |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1Vw6uGHAh-_DPQYu5vbWBOIlsiYdcqDHk/view?usp=drivesdk">https://drive.google.com/file/d/1Vw6uGHAh-_DPQYu5vbWBOIlsiYdcqDHk/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
