Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester)triblock copolymers and putrescine: synthesis, characterization and cytocompatibility (Record no. 48110)
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| fixed length control field | 02641nam a2200265Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625153931.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-13913 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester)triblock copolymers and putrescine: synthesis, characterization and cytocompatibility |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | BioMaterials, 25, p.85-96, 2004 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Polymers with elastomeric mechanical properties,tunable biodegradation properties and cytocompatibility would be desirable for numerous biomedical applications. Toward this end a series of biodegradable poly(ether ester urethane)urea elastomers (PEEUUs)based on poly(ether ester)triblock copolymers were synthesized and characterized. poly(ether ester)triblock copolymers were synthesized by ring-opening polymerization of e-caprolactone with polyethylene glycol (PEG). PEEUUs were synthesized from these triblock copolymers and butyl diisocyanate,with putrescine as a chain extender. PEEUUs exhibited low glass transition temperatures and possessed tensile strengths ranging from 8 to 20MPa and breaking strains from 325(percent)to 560(percent). Increasing PEG length or decreasing poly(caprolactone)length in the triblock segment increased PEEUU water absorption and biodegradation rate. Human umbilical vein endothelial cells cultured in a medium supplemented with PEEUU biodegradation solution suggested a lack of degradation product cytotoxicity. Endothelial cell adhesion to PEEUUs was less than 60 (percent)of tissue culture polystyrene and was inversely related to PEEUU hydrophilicity. Surface modification of PEEUUs with ammonia gas radio-frequency glow discharge and subsequent immobilization of the cell adhesion peptide Arg-Gly-Asp-Ser increased endothelial adhesion to a level equivalent to tissue culture polystyrene. These biodegradable PEEUUs thus possessed properties that would be amenable to applications where high strength and flexibility would be desirable and exhibited the potential for tuning with appropriate triblock segment selection and surface modification. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | BIODEGRADABLE POLYMER |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | POLY(ETHER ESTER URETHANE)UREA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | BIODEGRADATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SURFACE MODIFICATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CELL COMPATIBILITY |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jianjun Guan |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Michael, S.S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Beckman, E.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wagner, W.R. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/10kbCltegeGwIVNTeMzlrXgmCw70uqm4y/view?usp=drivesdk">https://drive.google.com/file/d/10kbCltegeGwIVNTeMzlrXgmCw70uqm4y/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-13913 | 25.06.2025 | 25.06.2025 | Documentos solicitados |