MARC details
| 000 -LEADER |
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| fixed length control field |
02372nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625153932.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-13962 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
The foreign body reaction to a biodegradable biomaterial differs between rats and mice |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Journal of Biomedical Materials Research, 52(3), p.439-446, 2000 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Before a biomaterial can be applied in the clinic, biocompatibility must be tested in in vivo models, by monitoring the foreign body reaction. In this study, we compared the foreign body reaction (FBR)to the biodegradable biomaterial hexamethylenediisocyanate crosslinked dermal sheep collagen (HDSC)between several strains of rats and mice. HDSC disks were implanted subcutaneously on the backs of AO, BN, F344, LEW, and PVG rats and on the backs of 129 SVEV, BALB/c, and C57BL/6 mice. Materials were explanted after 7, 14, 21, and 28 days and processed for (immuno)light and transmission electron microscopic evaluation. In all rat strains, giant cell formation and phagocytosis of HDSC bundles were comparable. In addition, in the PVG rat, many plasma cells infiltrated the HDSC disks. Only a few T cells were present in AO and PVG rats, whereas, in F344 and LEW rats, the presence of T cells was more pronounced. BN rats showed an intermediate T-cell infiltration. In mice, the FBR to HDSC was comparable between the different strains. Compared with rats, giant cell formation was limited, whereas stroma formation was more abundant. Phagocytosis of HDSC bundles rarely occurred in mice, whereas calcification was observed more often. It is concluded that the FBR to HDSC clearly differs between rats and mice. This has consequences for assessment studies on biocompatibility and also on fundamental biomaterial research. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FOREIGN BODY REACTION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
RAT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MOUSE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BIOMATERIAL |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CROSSLINKED DERMAL SHEEP COLLAGEN |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Khouw, I.M.S.L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Van Wachem,P.B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Molema, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Plantinga, J.A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
De Leij, L.F.M.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Van Luyn, M.J.A. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1oxOZ_1GjlTeOu2eVbCGzgLEvMRAssjLr/view?usp=drivesdk">https://drive.google.com/file/d/1oxOZ_1GjlTeOu2eVbCGzgLEvMRAssjLr/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
