Triazole fungicides and the selection of resistance to medical triazoles in the opportunistic mould Aspergillus fumigatus (Record no. 48445)

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fixed length control field 02077nam a2200265Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153938.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-14251
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245 10 - TITLE STATEMENT
Title Triazole fungicides and the selection of resistance to medical triazoles in the opportunistic mould Aspergillus fumigatus
490 0# - SERIES STATEMENT
Volume/sequential designation Pest Management Science, 69(2), p.165-170, 2012
520 3# - SUMMARY, ETC.
Summary, etc. Azole resistance is an emerging problem in the opportunistic mould Aspergillus fumigatus. The triazoles are the most important agents for themanagementof Aspergillus diseases in humans. Selection for acquired resistancemay occur in the hospital setting through exposure to high doses of azoles during azole therapy, but evidence is accumulating that A. fumigatus may become resistant to medical triazoles through environmental exposure to fungicides. The recovery of A. fumigatus isolates resistant to the medical triazoles from azole-naive patients as well as from the environment strongly indicates an environmental route of resistance selection. Molecule alignment studies have identified five fungicides that share a very similar molecule structure with the medical triazoles, and thus may have selected for mechanisms that confer resistance to both groups of compounds. It is important to explore further the presumed fungicide-driven route of resistance selection in order to implement effective preventive measures as the prevalence of azole resistance in A. fumigatus continues to increase and causes major challenges in themanagement of azole-resistant Aspergillus diseases.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ASPERGILLUS FUMIGATUS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRIAZOLES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RESISTANCE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DEMETHYLASE INHIBITORS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ASPERGILLOSIS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Verweij, P.E.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kema, G.H.J
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zwaan, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Melchers, W.J.G.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Ovgg3rTAs0P60_af353lD-oaxHbQXamI/view?usp=drivesdk">https://drive.google.com/file/d/1Ovgg3rTAs0P60_af353lD-oaxHbQXamI/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-14251 25.06.2025 25.06.2025 Documentos solicitados