DNA methylation: roles in mammalian development (Record no. 48554)

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control field MX-MdCICY
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control field 20250625153940.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-14361
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Title DNA methylation: roles in mammalian development
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Volume/sequential designation Nature Reviews Genetics, 14, p.204-220, 2013
520 3# - SUMMARY, ETC.
Summary, etc. DNA methylation is among the best studied epigenetic modifications and is essential to mammalian development. Although the methylation status of most CpG dinucleotides in the genome is stably propagated through mitosis, improvements to methods for measuring methylation have identified numerous regions in which it is dynamically regulated. In this Review, we discuss key concepts in the function of DNA methylation in mammals, stemming from more than two decades of research, including many recent studies that have elucidated when and where DNA methylation has a regulatory role in the genome. We include insights from early development, embryonic stem cells and adult lineages, particularly haematopoiesis, to highlight the general features of this modification as it participates in both global and localized epigenetic regulation
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Personal name Smith, Z.D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Meissner, A.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1XhQLTzIyoac4tZy-F2CwvaqZZaWUz1hj/view?usp=drivesdk">https://drive.google.com/file/d/1XhQLTzIyoac4tZy-F2CwvaqZZaWUz1hj/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-14361 25.06.2025 25.06.2025 Documentos solicitados