Biological principles for the effects of ethanol (Record no. 48581)

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fixed length control field 02087nam a2200301Ia 4500
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control field MX-MdCICY
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control field 20250625153940.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-14389
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245 10 - TITLE STATEMENT
Title Biological principles for the effects of ethanol
490 0# - SERIES STATEMENT
Volume/sequential designation Enzyme Microb. Technol., 11(3), p.130-153, 1989
520 3# - SUMMARY, ETC.
Summary, etc. Biological principles for the effects of ethanol are deduced from a study of some 60 different cell types ranging from bacteria, yeasts, and fungi to animal and plant cells. The direct effects of ethanol against metabolic pathways appears to be minimal, and the observed effects are more a reflection of ethanol metabolism rather than ethanol per se. Roles for NAD/NADH imbalances, acetaldehyde accumulation, and for the deactivation (i.e., switching off)of replicative processes emerge as central mechanisms. In the yeast-ethanol fermentation, it is suggested that the ability to avoid acetaldehyde accumulation is a prerequisite to so-called ethanol tolerance. Membrane-related effects due to ethanol are also involved. However, the spectrum of these effects may be such that different loci are involved at different ethanol concentrations. These effects are due to the polar, dielectric, and hydrogen-bond interactions of ethanol with membrane proteins and with the surface groups of the membrane. Competition for, and displacement of, bound cellular water will also occur. The so-called lipophilic effects of ethanol are shown to be minimal. Strategies and mechanisms for ethanol tolerance are discussed.
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Topical term or geographic name entry element ETHANOL; YEAST
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Topical term or geographic name entry element FUNGI
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Topical term or geographic name entry element PLANT CELL
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Topical term or geographic name entry element BACTERIA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ACETALDEHYDE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element INHIBITION
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Topical term or geographic name entry element TOXICITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ALCOHOL DEHYDROGENASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element REPLICATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MEMBRANE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DEACTIVATION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jones, R.P.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1sox7jrQ0tPvLjOcamU6MtilreGOaaPyr/view?usp=drivesdk">https://drive.google.com/file/d/1sox7jrQ0tPvLjOcamU6MtilreGOaaPyr/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-14389 25.06.2025 25.06.2025 Documentos solicitados