Relationship of chromosomal damage induced by caffeine to growth temperature and ATP level in proliferating cells (Record no. 48644)
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| fixed length control field | 02179nam a2200205Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625153941.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-14456 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Relationship of chromosomal damage induced by caffeine to growth temperature and ATP level in proliferating cells |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Mutation Research, 164(5), p.327-333, 1986 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Caffeine is known to induce chromosomal aberrations in proliferating cells when they are incubated during G 2 and mitotic prophase. In the present paper, this caffeine effect has been analyzed in Allium cepa root meristems growing at different culture temperatures under steady-state kinetics. Caffeine (1-10 mM)induces chromosomal aberrations in a dose-dependent manner, and the treatment efficiency correlates linearly with the square of caffeine concentration. The efficiency of caffeine incubations, within the range 5-25°C during equivalent cycle time periods has also been studied. It has been found that the lower the culture temperature, the higher the level of chromosomal aberrations. Moreover, at different temperatures, the level of chromosomal aberrations is a simple function of caffeine concentration and the ATP level. Therefore, the efficiency of caffeine treatment appears to be determined by some interaction between caffeine concentration and cellular ATP level. Our present results demonstrate that the influence of growth temperature on the chromosome-breaking effect of caffeine can be, at least partially, explained by the ATP levels during the incubation periods. In short, under different kinetics of plant cell proliferation, the ATP level, and/or something correlating with it, could explain the efficiency of caffeine in inducing chromosomal aberrations: the lower the ATP level, the higher the caffeine efficiency. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hernfindez, P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mingo, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gonzhlez-Fernhndez, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | López-Sfiez J.F. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1EVJSj9JrSQf2dbQnedEzED6_zDDJoaMW/view?usp=drivesdk">https://drive.google.com/file/d/1EVJSj9JrSQf2dbQnedEzED6_zDDJoaMW/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-14456 | 25.06.2025 | 25.06.2025 | Documentos solicitados |