Strengthening mechanisms of bone bonding to crystalline hydroxyapatite in vivo (Record no. 48674)

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fixed length control field 02632nam a2200277Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153942.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-14486
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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245 10 - TITLE STATEMENT
Title Strengthening mechanisms of bone bonding to crystalline hydroxyapatite in vivo
490 0# - SERIES STATEMENT
Volume/sequential designation BioMaterials, 25(18), p.4243-4254, 2004
520 3# - SUMMARY, ETC.
Summary, etc. The formation and strengthening mechanisms of bone bonding of crystalline hydroxyapatite (HA)has been investigated using high-resolution transmission electron microscope (HRTEM)and energy-dispersive X-ray (EDX)analysis.A series of results were obtained: (i)a layer of amorphous HA, which has almost the same chemistry as the implanted HA, was formed on the surface of crystalline HA particles prior to dissolution; (ii)at 3 months a bone-like tissue formed a bonding zone between mature bone and the HA implant, composed of nanocrystalline and amorphous apatite; and (iii)at 6 months, mature bone was in direct contact with HA particles, and collagen fibres were perpendicularly inserted into the surface layer of implanted HA crystals.Findings (i)and (ii)indicated the following dissolution-precipitation process.(i)The crystalline HA transforms into amorphous HA; (ii)the amorphous HA dissolves into the surrounding solution, resulting in over-saturation; and (iii)the nanocrystallites are precipitated from the oversaturated solution in the presence of collagen fibres.A preliminary analysis indicated several conclusions: (i)the transition from crystalline to amorphous HA might be the controlling step in the bone bonding of crystalline HA; (ii)biological interdigitation (or incorporation)of collagen fibres with HA and chemical bonding of a apatite layer were both necessary to strengthen and toughen a bone bond, not only for the bonding between bone and HA at 6 months, but also for the bonding zone at 3 months, which would otherwise be very fragile due to the inherited brittleness of polycrystalline ceramics; and (iii)perpendicular interdigitation is an effective way for collagen fibres to impart their unique combination of flexibility and strength to the interface which they are keying
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HYDROXYAPATITE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BONE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element INTERFACE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN VIVO
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HRTEM
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chen, Q.Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wong, C.T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lu, W.W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cheung, K.M.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Leong, J.C.Y.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1d0IgaTrXiGkkN_8CzhPXPQGga7Gxr-oL/view?usp=drivesdk">https://drive.google.com/file/d/1d0IgaTrXiGkkN_8CzhPXPQGga7Gxr-oL/view?usp=drivesdk</a>
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-14486 25.06.2025 25.06.2025 Documentos solicitados