Grafting of Gelatin on Electrospun Poly(caprolactone)Nanofibers to Improve Endothelial Cell Spreading and Proliferation and to Control Cell Orientation (Record no. 48726)
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| 000 -LEADER | |
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| fixed length control field | 02200nam a2200193Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625153943.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-14539 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Grafting of Gelatin on Electrospun Poly(caprolactone)Nanofibers to Improve Endothelial Cell Spreading and Proliferation and to Control Cell Orientation |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Tissue Engineering, 11(7-8), p.1149-1158, 2005 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | We modified the surface of electrospun poly(caprolactone)(PCL)nanofibers to improve their compatibility with endothelial cells (ECs)and to show the potential application of PCL nanofibers as a blood vessel tissue-engineering scaffold. Nonwoven PCL nanofibers (PCL NF)and aligned PCL nanofibers (APCL NF)were fabricated by electrospinning technology. To graft gelatin on the nanofiber surface, PCL nanofibers were first treated with air plasma to introduce -COOH groups on the surface, followed by covalent grafting of gelatin molecules, using water-soluble carbodiimide as the coupling agent. The chemical change in the material surface during surface modification was confirmed by X-ray photoelectron spectroscopy and quantified by colorimetric methods. ECs were cultured to evaluate the cytocompatibility of surface-modified PCL NF and APCL NF. Gelatin grafting can obviously enhance EC spreading and proliferation compared with the original material. Moreover, gelatin-grafted APCL NF readily orients ECs along the fibers whereas unmodified APCL NF does not. Immunostaining micrographs showed that ECs cultured on gelatin-grafted PCL NF were able to maintain the expression of three characteristic markers: platelet-endothelial cell adhesion molecule 1 (PECAM-1), intercellular adhesion molecule 1 (ICAM-1), and vascular cell adhesion molecule 1 (VCAM-1). The surface-modified PCL nanofibrous material is a potential candidate material in blood vessel tissue engineering. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ma, Z. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yong, T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ramakrishna, S. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1r9QZIQopVIBwWVRHubvW6eFTw4FuHFYE/view?usp=drivesdk">https://drive.google.com/file/d/1r9QZIQopVIBwWVRHubvW6eFTw4FuHFYE/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-14539 | 25.06.2025 | 25.06.2025 | Documentos solicitados |