MARC details
| 000 -LEADER |
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| fixed length control field |
03219nam a2200265Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625153943.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-14550 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Cervical spine fusion with bioabsorbable cages |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Neurosurg Focus, 16(3), p.1-10, 2004 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Object. Although it improves rates of fusion in surgical arthrodesis, conventional spinal instrumentation is associated with several risks, including hardware extrusion that injures adjacent anatomical structures, and disuse osteopenia as a result of stress shielding. The long-term effects of indwelling spinal instrumentation, although incompletely documented, may be detrimental. One way to avoid such problems would be to use bioabsorbable implantation devices. In this pilot study, performed in 1998 and 1999, the authors evaluated the use of a bioabsorbable interbody fusion device in a goat cervical spine model. Methods. Forty-two goats underwent two-level anterior cervical discectomy and fusion: eight received iliac crest autograft; 16 received a cage implant composed of 70:30 poly(L-lactide-co-D,L-lactide)/polyglycolic acid (70:30 PLDLLA/PGA)filled with either autograft or recombinant human bone morphogenetic protein-2 (rhBMP-2); and 18 received a cage implant composed of 85:15 PLDLLA/PGA filled with either autograft or rhBMP-2. Animals were killed at 3, 6, and 12 months postsurgery, and their cervical spines were evaluated histologically, radiographically, and physically for fusion. A primarily fibrous union was demonstrated in all animals killed at 3 months. At 6 months, bone trabeculae had become more prominent and the fibrous response less so in all cohorts. This occurred most frequently in the animals that underwent fusion with the 70:30 PLDLLA/PGA cages filled with rhBMP-2, in which 63 percent attained a histologically confirmed union that contained quantitatively more bone and less fibrous tissue than in the other cohorts; 63 percent of the unions in the aforementioned cohort were graded quantitatively as being stable. Conclusions. In this study the authors have established that the 85:15 PLDLLA/PGA cages are absorbed too quickly to be functionally useful in this model. The 70:30 PLDLLA/PGA cages worked as well as tricortical autograft when filled with cancellous autograft, and better when filled with rhBMP-2. At 6- and 12-month follow-up review, the 70:30 PLDLLA/PGA cages had not yet begun to be absorbed. There was little if any inflammatory response to these cages at 6 months. Future studies should include biomechanical and microradiographic testing, and a longer follow-up period is necessary in this model to determine when the 70:30 PLDLLA/PGA cages are absorbed. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BIOABSORBABLE IMPLANT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
POLYLACTIC ACID |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
POLYGLYCOLIC ACID |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SPINAL FUSION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CERVICAL SPINE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GOAT |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lippman, C.R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hajjar, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Abshire, B. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1TvPhiuP_oOwWz2qIsY1ecgOjP7cl-xeH/view?usp=drivesdk">https://drive.google.com/file/d/1TvPhiuP_oOwWz2qIsY1ecgOjP7cl-xeH/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
