Vitamin B12 metabolism in Mycobacterium tuberculosis (Record no. 49096)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01777nam a2200205Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625153950.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-14912 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Vitamin B12 metabolism in Mycobacterium tuberculosis |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Future MicroBiology, 8(11), p.1405-1418, 2013 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Mycobacterium tuberculosis is included among a select group of bacteria possessing the capacity for de novobiosynthesis of vitamin B12 , the largest and most complex natural organometallic cofactor. The bacillus is also able to scavenge B 12 and related corrinoids utilizing an ATP-binding cassette-type protein that is distinct from the only known bacterial B 12 -specific transporter, BtuFCD. Consistent with the inferred requirement for itamin B12 for metabolic function, the M. tuberculosisgenome encodes two B12 riboswitches and three B 12 -dependent enzymes. Two of these enzymes have been shown to operate in methionine biosynthesis (MetH)and propionate utilization (MutAB), while the function of the putative nrdZ-encoded ribonucleotide reductase remains unknown. Taken together, these observations suggest that M. tuberculosis has the capacity to regulate core metabolic functions according to B 12 availability - whether acquired via endogenous synthesis or through uptake from the host environment - and, therefore, imply that there is a role for vitamin B12 in pathogenesis, which remains poorly understood. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gopinath, K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moosa, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mizrahi, V. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Warner, D.F. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1wUGQUqyoMDpuF2NuKyXq090HB1BbNCft/view?usp=drivesdk">https://drive.google.com/file/d/1wUGQUqyoMDpuF2NuKyXq090HB1BbNCft/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-14912 | 25.06.2025 | 25.06.2025 | Documentos solicitados |