Chemical and biological study of Manilkara zapota (L.)Van Royen leaves (Sapotaceae)cultivated in Egypt (Record no. 49697)

MARC details
000 -LEADER
fixed length control field 02697nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160134.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-15517
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Chemical and biological study of Manilkara zapota (L.)Van Royen leaves (Sapotaceae)cultivated in Egypt
490 0# - SERIES STATEMENT
Volume/sequential designation Pharmacognosy Research, 4(2), p.85-91, 2012
520 3# - SUMMARY, ETC.
Summary, etc. Background: Manilkara zapota (L.)Van Royen is an evergreen tree, native to the tropical Americas and introduced to Egypt as a fruiting tree in 2002. No previous study was reported on the plant cultivated in Egypt. Materials and Methods: In this study, the leaves of the plant cultivated in Egypt were subjected to phytochemical and biological investigations. The lipoidal matter was analyzed by GLC. Five compounds were isolated from the petroleum ether and ethyl acetate fractions of the alcoholic extract of the leaves by chromatographic fractionation on silica gel and sephadex, the structures of these compounds were identified using IR, UV, MS,H-NMR and 13 PHCOG RES. C-NMR. The LD of the alcoholic and aqueous extracts of the leaves was determined and their antihyperglycemic, hypocholesterolemic and antioxidant activities were tested by enzymatic colorimetric methods using specific kits. Results: Unsaturated fatty acids represent 32.32 percent of the total fatty acids, oleic acid (13.95 percent), linoleidic acid (10.18 percent)and linoleic acid (5.96 percent)were the major ones. The isolated compounds were identified as lupeol acetate, oleanolic acid, apigenin-7-O-a-L-rhamnoside, myricetin-3-O-a-L-rhamnoside and caffeic acid. This is the first report about isolation of these compounds from Manilkara zapota cept myricetin-3-O-a-Lrhamnoside, which was previously isolated from the plant growing abroad. The LD 50 recorded 80 g/Kg b. wt. for both the tested extracts, so they could be considered to be safe. They exhibited antihyperglycemic, hypocholesterolemic and antioxidant activities. Conclusion: The observed biological activities were attributed to the different chemical constituents present in the plant mainly its phenolic constituents.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIHYPERGLYCEMIC
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HYPOCHOLESTEROLEMIC
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIOXIDANT
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element FLAVONOIDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MANILKARA ZAPOTA (L.)VAN ROYEN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRITERPENES
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Fayek, N.M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Monem, A.R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mossa, M.Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Meselhy, M.R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shazly A.H.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1GCIfHqb1Xqxm0oq38s2m3O9qtOZFqb8D/view?usp=drivesdk">https://drive.google.com/file/d/1GCIfHqb1Xqxm0oq38s2m3O9qtOZFqb8D/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-15517 25.06.2025 25.06.2025 Documentos solicitados