Common origins of RNA, protein and lipid precursors in a cyanosul?dic protometabolism (Record no. 49760)
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| fixed length control field | 01753nam a2200217Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625160135.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-15580 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Common origins of RNA, protein and lipid precursors in a cyanosul?dic protometabolism |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Nature Chemistry, 7, p.301-307, 2015 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | A minimal cell can be thought of as comprising informational, compartment-forming and metabolic subsystems. To imagine the abiotic assembly of such an overall system, however, places great demands on hypothetical prebiotic chemistry. The perceived differences and incompatibilities between these subsystems have led to the widely held assumption that one or other subsystem must have preceded the others. Here we experimentally investigate the validity of this assumption by examining the assembly of various biomolecular building blocks from prebiotically plausible intermediates and one-carbon feedstock molecules. We show that precursors of ribonucleotides, amino acids and lipids can all be derived by the reductive homologation of hydrogen cyanide and some of its derivatives, and thus that all the cellular subsystems could have arisen simultaneously through common chemistry. The key reaction steps are driven by ultraviolet light, use hydrogen sul?de as the reductant and can be accelerated by Cu(I)-Cu(II)photoredox cycling. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel, B.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Percivalle, C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ritson, D.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Duffy, C.D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sutherland, J.D. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1ZW34Whye4MFdSddjGbeExFaQUdSGX7yb/view?usp=drivesdk">https://drive.google.com/file/d/1ZW34Whye4MFdSddjGbeExFaQUdSGX7yb/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-15580 | 25.06.2025 | 25.06.2025 | Documentos solicitados |