In Vivo Evaluation of a Porous, Elastic, Biodegradable Patch for Reconstructive Cardiac Procedures (Record no. 50125)

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control field 20250625160142.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-15949
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Title In Vivo Evaluation of a Porous, Elastic, Biodegradable Patch for Reconstructive Cardiac Procedures
490 0# - SERIES STATEMENT
Volume/sequential designation Annals of Thoracic Surgery, 83(2), p.648-654, 2007
520 3# - SUMMARY, ETC.
Summary, etc. Purpose: Several synthetic materials have been used for cardiac reconstruction in patients with complex congenital heart defects. These materials are not viable, do not grow with children, and may necessitate reoperation. We report here on the cardiac implantation of a recently developed, degradable porous material designed to facilitate cellular ingrowth during the healing process. Description: An elastomeric, biodegradable polyester urethane urea (PEUU)was processed into circular scaffolds and used to replace a surgical defect in the right ventricular outflow tract of adult rats. Control rats were implanted with expanded polytetrafluoroethylene. Histologic evaluation was performed at 4, 8, and 12 weeks postsurgery. Evaluation: All animals survived the surgery. Both PEUU and expanded polytetrafluoroethylene were encapsulated with fibrous tissue and had complete endothelialization on the endocardial surface with no aneurysm formation or thrombus noted. With PEUU patching, fibroblast ingrowth occurred at 4 weeks, increasing with time. In contrast, expanded polytetrafluoroethylene patches exhibited no ingrowth and elicited local inflammation that moderated with time. Conclusions: The PEUU patch demonstrated suitable mechanical properties and biocompatible characteristics in the right ventricular outflow tract replacement model, permitting cellular integration and endocardial endothelialization with minimal inflammation. Future application of this material as a cardiovascular scaffold seems promising. © 2007 The Society of Thoracic Surgeons.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLITEF
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYESTER URETHANE UREA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYMER
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element UNCLASSIFIED DRUG
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Fujimoto, K.L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Guan, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Oshima, H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sakai, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wagner, W.R.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1YFuRhycFmLL3Opd2xuugppH2UsOeBfKh/view?usp=drivesdk">https://drive.google.com/file/d/1YFuRhycFmLL3Opd2xuugppH2UsOeBfKh/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-15949 25.06.2025 25.06.2025 Documentos solicitados