MARC details
| 000 -LEADER |
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| fixed length control field |
02996nam a2200361Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625160144.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-16073 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Oxidative biodegradation mechanisms of biaxially strained poly(etherurethane urea)elastomers |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Journal of Biomedical Materials Research, 29(3), p.337-347, 1995 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
As part of ongoing studies in polyurethane biostability and biodegradation, we have investigated an in vitro system to test strained poly(etherurethane urea)(PEUU). Recently, we utilized this system to reproduce in vivo stress cracking in strained Pellethane®. In this study, strained PEUU was tested to determine whether it degrades through a common mechanism with Pellethane® and to further examine the steps involved in this degradation. Biaxially strained PEUU elastomers were treated with an a2- macroglobulin (a2-Mac)protein solution followed by an oxidative H2O2/CoCl2 treatment. Characterization of the strained PEUU specimens was performed with attenuated total reflectance-Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), electron spectroscopy for chemical analysis, and contact angle analysis. The re-suits from these characterization techniques provide conclusive evidence that biodegradation of PEUU and Pellethane® occurs through a common mechanism. Chemical changes to the PEUU include cleavage of the polyether soft segments and urethane linkages, leaving the hard segment domains unaffected. SEM analysis shows that this chain cleavage leads to the development of severe pitting and cracking of the PEUU surface. In addition, the in vitro degradation accurately reproduces the in vivo degradation chemically and physically. This result verifies that the primary species responsible for biodegradation of PEUUs, in vivo, are hydroxyl and/or hydroperoxide radicals. a2-Mac pretreatment increases the rate of degradation compared to direct treatment in H2O2/CoCl2. As the PEUU soft segment chains are cleaved, the degradation products are extracted into the treatment solution or environment. Finally, a new biodegradation mechanism of PEUUs is presented that involves crosslinking of the polyether soft segments. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ADSORPTION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BIODEGRADATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CONTACT ANGLE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CROSSLINKING |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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DEGRADATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ELASTOMERS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ELECTRON SPECTROSCOPY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FOURIER TRANSFORM INFRARED SPECTROSCOPY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
POLYETHERS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SCANNING ELECTRON MICROSCOPY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
STRAIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
UREA |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Schubert, M.A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wiggins, M.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Schaefer, M.P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hiltner, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Anderson, J.M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1iIAjOWNOokemNrH1UhW_uuuLBGexjruN/view?usp=drivesdk">https://drive.google.com/file/d/1iIAjOWNOokemNrH1UhW_uuuLBGexjruN/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
