Compartmentalization of cAMP signaling in adipogenesis, lipogenesis, and lipolysis (Record no. 50332)

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fixed length control field 02137nam a2200301Ia 4500
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160146.0
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Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-16158
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245 10 - TITLE STATEMENT
Title Compartmentalization of cAMP signaling in adipogenesis, lipogenesis, and lipolysis
490 0# - SERIES STATEMENT
Volume/sequential designation Hormone and Metabolic Research, 46(12), p.833-840, 2014
520 3# - SUMMARY, ETC.
Summary, etc. Energy storage and release at times of food excess or fasting are carefully coordinated processes that depend on the appropriate differentiation of mesenchymal stem cells into mature adipocytes (adipogenesis)forming white adipose tissue (WAT)and on regulatory signals for storage (lipogenesis)or mobilization (lipolysis)of triacylglycerides (TAGs)from lipid droplets. It is widely recognized that cAMP signaling via protein kinase A (PKA)is important both in adipogenesis and for hormonal control and lipolysis in WAT. A kinase anchoring proteins (AKAPs)target PKA to distinct subcellular compartments in close proximity to its specific substrates thereby providing spatial and temporal specificity in the mediation of biological effects controlled by the cAMP-PKA pathway. This review will provide an updated overview of some of the sites of regulation by cAMP in adipogenesis and lipolysis and the involvement of AKAPs and highlighting, as a recent example, the AKAP Optical Atrophy 1 (OPA1)and its role in the phosphorylation of Perilipin to induce lipolysis.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element YCLIC AMP
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYCLIC AMP DEPENDENT PROTEIN KINASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element FAT DROPLET
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HORMONE SENSITIVE LIPASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PERILIPIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRIACYLGLYCEROL LIPASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYCLIC AMP
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rogne, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tasken, K.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1QN6Vr-TExJ1jz7lQrSMrhZetVTjdrsJg/view?usp=drivesdk">https://drive.google.com/file/d/1QN6Vr-TExJ1jz7lQrSMrhZetVTjdrsJg/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-16158 25.06.2025 25.06.2025 Documentos solicitados