Co-Delivery of Cell-Wall-Forming enzymes in the same vesicle for coordinated fungal cell wall formation (Record no. 50359)
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| fixed length control field | 02166nam a2200253Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625160146.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-16185 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Co-Delivery of Cell-Wall-Forming enzymes in the same vesicle for coordinated fungal cell wall formation |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Nature MicroBiology, 1(11), p.1-11, 2016 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Fungal cells are surrounded by an extracellular cell wall. This complex matrix of proteins and polysaccharides protects against adverse stresses and determines the shape of fungal cells. The polysaccharides of the fungal wall include 1,3-ß-glucan and chitin, which are synthesized by membrane-bound synthases at the growing cell tip. A hallmark of filamentous fungi is the class V chitin synthase, which carries a myosin-motor domain. In the corn smut fungus Ustilago maydis, the myosin-chitin synthase Mcs1 moves to the plasma membrane in secretory vesicles, being delivered by kinesin-1 and myosin-5. The myosin domain of Mcs1 enhances polar secretion by tethering vesicles at the site of exocytosis. It remains elusive, however, how other cell-wall-forming enzymes are delivered and how their activity is coordinated post secretion. Here, we show that the U. maydis class VII chitin synthase and 1,3-ß-glucan synthase travel in Mcs1-containing vesicles, and that their apical secretion depends on Mcs1. Once in the plasma membrane, anchorage requires enzyme activity, which suggests co-synthesis of chitin and 1,3-ß-glucan polysaccharides at sites of exocytosis. Thus, delivery of cell-wall-forming enzymes in Mcs1 vesicles ensures local foci of fungal cell wall formation. © 2016 Macmillan Publishers Limited, part of Springer Nature. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | FUNGAL CELLS |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schuster, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Martin-Urdiroz, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Higuchi, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hacker, C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kilaru, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gurr, S.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Steinberg, G. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1Ns-ojNl2kVBTSX_9ETvZJhU4u3Y0vdv4/view?usp=drivesdk">https://drive.google.com/file/d/1Ns-ojNl2kVBTSX_9ETvZJhU4u3Y0vdv4/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-16185 | 25.06.2025 | 25.06.2025 | Documentos solicitados |