MARC details
| 000 -LEADER |
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| fixed length control field |
02556nam a2200373Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625160149.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-16349 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Protective and antioxidant effects of Rhizophora mangle L. against NSAID-induced gastric ulcers |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Journal of EthnoPharmacology, 103(2), p.194-200, 2006 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
The bark of Rhizophora mangle, the red mangrove, has been used traditionally in folk medicine of Caribbean countries due to its antiseptic, astringent, haemostatic and antifungal properties. Aqueous extracts are rich in tannins and have been proven experimentally to possess antibacterial, wound healing and antiulcerogenic effects. This work was designed to determine the gastroprotective effect of Rhizophora mangle in a model of diclofenac-induced ulcers in rats and to study the mechanisms involved, using the proton pump inhibitor omeprazole as a comparison. The lyophilized extract was given by oral gavage (125 and 62.5 mg/kg)three times at 12 h intervals before administering diclofenac 100 mg/kg. Pretreatment with the extract resulted in a significant decrease of the ulcerated area (P lt; 0.01). Rhizophora mangle induced a recovery of PGE2 levels, which had been depleted by diclofenac. No anti-inflammatory effect was observed ex vivo or in vitro. The highest dose of the extract provoked a marked increase in glutathione peroxidase and superoxide dismutase activity, which was comparable to omeprazole. Furthermore, lipid peroxidation levels were inhibited in a dose-dependent manner. These results suggest that the gastroprotective effect of Rhizophora mangle in this experimental model appears through an antioxidant and prostaglandin-dependent way. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTIOXIDANT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
DICLOFENAC |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GLUTATHIONE PEROXIDASE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
NONSTEROID ANTIINFLAMMATORY AGENT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
OMEPRAZOLE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PLANT EXTRACT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PROSTAGLANDIN E2 |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PROTON PUMP INHIBITOR |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
RHIZOPHORA MANGLE EXTRACT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SUPEROXIDE DISMUTASE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
UNCLASSIFIED DRUG |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Berenguer, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Sánchez, L.M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Quílez, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
López-Barreiro, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
De Haro, O |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Gálvez, J |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Martín, M.J. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1dcOchRBDbQS31ch_zxJW0wcrDjE4qace/view?usp=drivesdk">https://drive.google.com/file/d/1dcOchRBDbQS31ch_zxJW0wcrDjE4qace/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
