MARC details
| 000 -LEADER |
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| fixed length control field |
02365nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625160152.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-16492 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
A novel anticandidal compound containing sulfur from endophytic Fungus emericella sp |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Natural Products Journal, 6(3), p.188-193, 2016 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Background: Endophtes live symbiotically in the tissues of host plants without causing visible harm. These endophytes produce not only the plant bioactive metabolites but also a host of unexplored structurally diverse natural products having biological activity. New niches may be explored for bioprospecting endophytes for the development of novel candidate molecules having industrial applications. Methods: The bioactive compound is isolated from the endophyte Emericella sp. associated with Azadirachta indica A. Juss (Neem), that potentially inhibits or prevents the human pathogenic disease caused by Candida albicans. The molecule was characterized by employing TLC, IR and GCMS. The isolated compound was identified as N-[(2S, 3aR, 6S, 7aS)-6-acetamido-octahydro-1,3-benzothiazol-2-yl]2- (adamantan-1-yl)acetamide having sulfur. Results: In the present study, a new molecule containing sulphur inhibits the growth of Candida specifically. The molecule can serve as a lead molecule for designing new drugs having anticandidal activity. The compound having anticandidal activity belongs to the class of antifungal agent - allylamine, azole and polyene. Conclusion: A new molecule containing sulphur and inhibiting specifically C. albicans is reported in the present study. They are known to promote plant growth and yield, act as biocontrol agents and are known to produce secondary metabolites, such as enzymes, growth hormones, antimicrobial, antifungal, or anticancerous substances. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTICANDIDAL DRUG |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
AZADIRACHTA INDICA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CANDIDA ALBICANS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
EMERICELLA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ENDOPHYTE |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mittal, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Shrivastava, D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Govil, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kumar, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Bisen, P.S. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1_B68MD7KSyq2W12EHdoXxCN8T4zX1B53/view?usp=drivesdk">https://drive.google.com/file/d/1_B68MD7KSyq2W12EHdoXxCN8T4zX1B53/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
