Human plasma alpha 2-macroglobulin promotes in vitro oxidative stress cracking of Pellethane 2363-80A: in vivo and in vitro correlations. (Record no. 50791)

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control field MX-MdCICY
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control field 20250625160155.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-16621
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Title Human plasma alpha 2-macroglobulin promotes in vitro oxidative stress cracking of Pellethane 2363-80A: in vivo and in vitro correlations.
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Volume/sequential designation J Biomed Mater Res., 27(3), p.379-388, 1993
520 3# - SUMMARY, ETC.
Summary, etc. It is hypothesized in this study that the phenomenon of environmental stress cracking (ESC)in polyetherurethane is caused by a synergistic action of biological components in the body fluids, oxidative agents, and stress. An in vitro system is designed to mimic the in vivo system; human plasma contains certain biological components that can act as a stress cracking promoter, while H2O2 (Co)solution provides an oxidative reaction comparable to that observed in the respiratory burst of adherent macrophages and foreign-body giant cells. It is demonstrated that the phenomenon of in vivo stress cracking in Pellethane 2363-80A is duplicated by an in vitro system that involves a pretreatment of prestressed specimens with human plasma at 37 degrees C for 7 days followed by oxidation in 10 percent hydrogen peroxide with 0.10M cobalt chloride at 50 degrees C for 10 days. The pretreatment with plasma has a synergistic effect with the oxidation by H2O2 (Co)treatment to produce ESC. A plasma component responsible for promoting stress cracking in Pellethane polyurethane is identified to be alpha 2-macroglobulin (alpha 2M).
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Topical term or geographic name entry element PLASMA
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zhao Qh
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mcnally Ak
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Personal name Rubin Kr
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Personal name Renier M
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Personal name Wu Y
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Personal name Rose-Caprara V
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Personal name Anderson Jm
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Anderson Jm
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Personal name Urbanski P
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Stokes K
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/18xd-bV3KV9odW_y6b-bq6visYSHTpsmi/view?usp=drivesdk">https://drive.google.com/file/d/18xd-bV3KV9odW_y6b-bq6visYSHTpsmi/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-16621 25.06.2025 25.06.2025 Documentos solicitados