Insect cytochromes P450: Diversity, insecticide resistance and tolerance to plant toxins (Record no. 50882)
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| 000 -LEADER | |
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| fixed length control field | 02834nam a2200253Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625160156.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-16712 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Insect cytochromes P450: Diversity, insecticide resistance and tolerance to plant toxins |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Comparative BioChemistry and Physiology - C Pharmacology Toxicology and Endocrinology, 121(1-3), p.147-155, 1998 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | In the last decade, studies of individual insect P450s have blossomed. This new information has furthered our understanding of P450 diversity, insecticide resistance and tolerance to plant toxins. Insect P450s can be adult specific, larval specific or life stage independent. Similarly, insect P450s vary as to the tissues where they are expressed and in their response to inducers. Insect P450s can now be rapidly sequenced using degenerate PCR primers. Given the huge diversity represented by the Class Insecta, this technique will provide vast amounts of new information about insect P450s and the evolution of the P450 gene superfamily. CYP6D1 is responsible for monooxygenase-mediated resistance to pyrethroid insecticides in the house fly. CYP6D1 is ubiquitously expressed in adults with 10-fold higher levels found in the resistant strain compared to susceptible strains. CYP6D1 is on autosome 1 in house fly. The high level of expression found in the resistant strain is due to genes on autosomes 1 and 2. Whether or not the different CYP6D1 alleles found in resistant and susceptible strains have any role in resistance remains to be elucidated. The CYP6B gene subfamily is involved in the metabolism of host plant toxins (i.e. furanocoumarins). CYP6B gene transcripts in two Papilio (swallowtail)species have been shown to be induced by host plant toxins and in turn to metabolize these toxins. CYP6B P450s play a critical role in allowing Papilio to adapt to furanocoumarin-containing host plants. Similarities in structural and promoter regions of the CYP6B genes suggest that they are derived from a common ancestral gene. Although the P450 monooxygenases of insects are important for the metabolism of hormones and pheromones, no individual P450 has yet been shown to metabolize an endogenous compound. Advances in this area are critical because they will provide important new information about insect physiology, biochemistry and development. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CYTOCHROME P450 ISOENZYME |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | INSECTICIDE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PHEROMONE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PLANT TOXIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PYRETHROID |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Scott, J.G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wen, Z. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/14JGDQWYY8QEo-Sh0RjSzA_lWCV4wVOpH/view?usp=drivesdk">https://drive.google.com/file/d/14JGDQWYY8QEo-Sh0RjSzA_lWCV4wVOpH/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-16712 | 25.06.2025 | 25.06.2025 | Documentos solicitados |