CRISPR/Cas9-Based Engineering of the Epigenome (Record no. 50892)

MARC details
000 -LEADER
fixed length control field 01892nam a2200301Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160156.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-16725
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245 10 - TITLE STATEMENT
Title CRISPR/Cas9-Based Engineering of the Epigenome
490 0# - SERIES STATEMENT
Volume/sequential designation Cell Stem Cell, 21(4), p.431-447, 2017
520 3# - SUMMARY, ETC.
Summary, etc. Determining causal relationships between distinct chromatin features and gene expression, and ultimately cell behavior, remains a major challenge. Recent developments in targetable epigenome-editing tools enable us to assign direct transcriptional and functional consequences to locus-specific chromatin modifications. This Protocol Review discusses the unprecedented opportunity that CRISPR/Cas9 technology offers for investigating and manipulating the epigenome to facilitate further understanding of stem cell biology and engineering of stem cells for therapeutic applications. We also provide technical considerations for standardization and further improvement of the CRISPR/Cas9-based tools to engineer the epigenome. Pulecio et al. discuss opportunities that CRISPR/Cas9 technology offers for investigating and manipulating the stem cell epigenome and also provide technical considerations for CRISPR/Cas9 tool standardization and improvement.
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Topical term or geographic name entry element CHROMATIN ARCHITECTURE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CRISPR-DCAS9
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DNA METHYLATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HISTONE MODIFICATIONS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TARGETED EPIGENOME ENGINEERING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TARGETED GENE EDITION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRANSCRIPTIONAL REGULATION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Pulecio, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Verma, N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mejía-Ramírez, E.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Huangfu, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Raya, A.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1l-BWzjRzu5kw0dUsVT6H0tBDuwqkBe6Y/view?usp=drivesdk">https://drive.google.com/file/d/1l-BWzjRzu5kw0dUsVT6H0tBDuwqkBe6Y/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-16725 25.06.2025 25.06.2025 Documentos solicitados