The Biology of CRISPR-Cas: Backward and Forward (Record no. 51149)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01630nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625160201.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-16984 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | The Biology of CRISPR-Cas: Backward and Forward |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Cell, 172(6), p.1239-1259, 2018 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR)and CRISPR-associated (Cas)proteins constitute an adaptive immune system against phages and other foreign genetic elements. Here, we review the biology of the diverse CRISPR-Cas systems and the major progress achieved in recent years in understanding the underlying mechanisms of the three stages of CRISPR-Cas immunity: adaptation, crRNA biogenesis, and interference. The ecology and regulation of CRISPR-Cas in the context of phage infection, the roles of these systems beyond immunity, and the open questions that propel the field forward are also discussed. CRISPR-Cas systems provide bacteria and archaea with diverse mechanisms of adaptive immunity, illuminating the evolutionary pressures imposed by selfish genetic elements. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CRISPR ASSOCIATED PROTEIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | NUCLEIC ACID |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hille, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Richter, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wong, S.P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bratovic, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ressel, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Charpentier, E. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1DJd2qHDOtUMwaBAbWc7VwI8Wq6S-ulDe/view?usp=drivesdk">https://drive.google.com/file/d/1DJd2qHDOtUMwaBAbWc7VwI8Wq6S-ulDe/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-16984 | 25.06.2025 | 25.06.2025 | Documentos solicitados |