Opposite roles of salicylic acid receptors NPR1 and NPR3/NPR4 in transcriptional regulation of plant immunity (Record no. 51175)
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| 000 -LEADER | |
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| fixed length control field | 01961nam a2200253Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625160202.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-17011 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Opposite roles of salicylic acid receptors NPR1 and NPR3/NPR4 in transcriptional regulation of plant immunity |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Cell, 173(6), p.1454-1467.e10, 2018 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Salicylic acid (SA)is a plant defense hormone required for immunity. Arabidopsis NPR1 and NPR3/NPR4 were previously shown to bind SA and all three proteins were proposed as SA receptors. NPR1 functions as a transcriptional co-activator, whereas NPR3/NPR4 were suggested to function as E3 ligases that promote NPR1 degradation. Here we report that NPR3/NPR4 function as transcriptional co-repressors and SA inhibits their activities to promote the expression of downstream immune regulators. npr4-4D, a gain-of-function npr4 allele that renders NPR4 unable to bind SA, constitutively represses SA-induced immune responses. In contrast, the equivalent mutation in NPR1 abolishes its ability to bind SA and promote SA-induced defense gene expression. Further analysis revealed that NPR3/NPR4 and NPR1 function independently to regulate SA-induced immune responses. Our study indicates that both NPR1 and NPR3/NPR4 are bona fide SA receptors, but play opposite roles in transcriptional regulation of SA-induced defense gene expression. Salicylic acid receptors NPR1 and NPR3/NPR4 play opposite roles in the transcriptional regulation of plant defense against pathogens. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SALICYLIC ACID |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ding, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sun, T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ao, K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Peng, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Y. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1Tk7R8JpLHKfOfbnR0dRjNe_NvodhFUyR/view?usp=drivesdk">https://drive.google.com/file/d/1Tk7R8JpLHKfOfbnR0dRjNe_NvodhFUyR/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-17011 | 25.06.2025 | 25.06.2025 | Documentos solicitados |