The DNA methyltransferase family: a versatile toolkit for epigenetic regulation (Record no. 51366)

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fixed length control field 01606nam a2200229Ia 4500
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control field MX-MdCICY
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control field 20250625160206.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-17203
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Title The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
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Volume/sequential designation Nature Reviews Genetics, 19(2), p.81, 2018
520 3# - SUMMARY, ETC.
Summary, etc. The DNA methyltransferase (DNMT)family comprises a conserved set of DNA-modifying enzymes that have a central role in epigenetic gene regulation. Recent studies have shown that the functions of the canonical DNMT enzymes-DNMT1, DNMT3A and DNMT3B-go beyond their traditional roles of establishing and maintaining DNA methylation patterns. This Review analyses how molecular interactions and changes in gene copy numbers modulate the activity of DNMTs in diverse gene regulatory functions, including transcriptional silencing, transcriptional activation and post-transcriptional regulation by DNMT2-dependent tRNA methylation. This mechanistic diversity enables the DNMT family to function as a versatile toolkit for epigenetic regulation. © 2018 Macmillan Publishers Limited, part of Springer Nature.
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Topical term or geographic name entry element DNA (CYTOSINE 5)METHYLTRANSFERASE 1
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DNA METHYLTRANSFERASE
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Topical term or geographic name entry element DNA METHYLTRANSFERASE 3ª
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DNA METHYLTRANSFERASE 3
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BHISTONE DEACETYLASE 2
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Personal name Lyko, F.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1QIW4Hufv7rxTtlD_BnWUCxTATTR27hwf/view?usp=drivesdk">https://drive.google.com/file/d/1QIW4Hufv7rxTtlD_BnWUCxTATTR27hwf/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-17203 25.06.2025 25.06.2025 Documentos solicitados