Spatially controlled cell engineering on biodegradable polymer surfaces (Record no. 51430)
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| fixed length control field | 02521nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625160207.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-17267 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Spatially controlled cell engineering on biodegradable polymer surfaces |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | The FASEB Journal, 12(14), p.1447-1454, 1998 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Controlling receptor-mediated interactions between cells and template surfaces is a central principle in many tissue engineering procedures (1-3). Biomaterial surfaces engineered to present cell adhesion ligands undergo integrin-mediated molecular interactions with cells (1, 4, 5), stimulating cell spreading, and differentiation (6-8). This provides a mechanism for mimicking natural cell-to-matrix interactions. Further sophistication in the control of cell interactions can be achieved by fabricating surfaces on which the spatial distribution of ligands is restricted to micron-scale pattern features (9-14). Patterning technology promises to facilitate spatially controlled tissue engineering with applications in the regeneration of highly organized tissues. These new applications require the formation of ligand patterns on biocompatible and biodegradable templates, which control tissue regeneration processes, before removal by metabolism. We have developed a method of generating micron-scale patterns of any biotinylated ligand on the surface of a biodegradable block copolymer, polylactide-poly(ethylene glycol). The technique achieves control of biomolecule deposition with nanometer precision. Spatial control over cell development has been observed when using these templates to culture bovine aortic endothelial cells and PC12 nerve cells. Furthermore, neurite extension on the biodegradable polymer surface is directed by pattern features composed of peptides containing the IKVAV sequence (15, 16), suggesting that directional control over nerve regeneration on biodegradable biomaterials can be achieved. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | INTEGRINS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | NEURITE EXTENSIÓN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PATTERNING |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | TISSUE ENGINEERING |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Padera, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanders, G. H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cannizzaro, S. M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Davies, M. C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Langer, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shakesheff, K. M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/17HAjbWtj9JKAigg6e3J6pVlkr5SA786p/view?usp=drivesdk">https://drive.google.com/file/d/17HAjbWtj9JKAigg6e3J6pVlkr5SA786p/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-17267 | 25.06.2025 | 25.06.2025 | Documentos solicitados |