MARC details
| 000 -LEADER |
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| fixed length control field |
02347nam a2200433Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625160210.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-17416 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
A Phytophthora effector suppresses trans-kingdom RNAi to promote disease susceptibility. |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Cell Host & Microbe, 25(1), p.153-165, 2019 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
RNA silencing (RNAi)has a well-established role in anti-viral immunity in plants. The destructive eukaryotic pathogen Phytophthora encodes suppressors of RNAi (PSRs), which enhance plant susceptibility. However, the role of small RNAs in defense against eukaryotic pathogens is unclear. Here, we show that Phytophthora infection of Arabidopsis leads to increased production of a diverse pool of secondary small interfering RNAs (siRNAs). Instead of regulating endogenous plant genes, these siRNAs are found in extracellular vesicles and likely silence target genes in Phytophthora during natural infection. Introduction of a plant siRNA in Phytophthora leads to developmental deficiency and abolishes virulence, while Arabidopsis mutants defective in secondary siRNA biogenesis are hypersusceptible. Notably, Phytophthora effector PSR2 specifically inhibits secondary siRNA biogenesis in Arabidopsis and promotes infection. These findings uncover the role of siRNAs as antimicrobial agents against eukaryotic pathogens and highlight a defense/counter-defense arms race centered on trans-kingdom gene silencing between hosts and pathogens. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTI-VIRAL IMMUNITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PHYTOPHTHORA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ARABIDOPSI |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SMALL INTERFERING RNAS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PLANT GENES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SIRNA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
VIRULENCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BIOGENESIS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GENE SILENCING |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hou, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zhai, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Feng, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Karimi, H. Z. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Rutter, B. D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zeng, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Seokchoi, D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Seokchoi, D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Gu, W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Chen, X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ye, W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Roger, W.I. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zhai, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ma, W. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1RZpC86SDLYNhFQi80A0s0M3NC6uVYlVj/view?usp=drivesdk">https://drive.google.com/file/d/1RZpC86SDLYNhFQi80A0s0M3NC6uVYlVj/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
