Quorum sensing pathways in Gram-positive and-negative bacteria: potential of their interruption in abating drug resistance. (Record no. 51991)

MARC details
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control field MX-MdCICY
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control field 20250625160218.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-17830
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Title Quorum sensing pathways in Gram-positive and-negative bacteria: potential of their interruption in abating drug resistance.
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Volume/sequential designation Journal of Chemotherapy, 31(4), p.161-187, 2019
520 3# - SUMMARY, ETC.
Summary, etc. Quorum sensing (QS)is an inter-cell communication between bacterial populations through release of tiny diffusible compounds as signalling agents, called auto-inducers, abetting bacteria to track population density. QS allows bacterial population to perform collectively in coordination to wide phenotypes like alterations in expression of virulence genes to achieve advancement over their competitors, drug resistance and biofilm formation. Several classes of autoinducers have been described that are involved in bacterial virulence. This review gives an insight into the multitudinous QS systems in Gram-positive and Gram-negative bacteria to explore their role in microbial physiology and pathogenesis. Bacterial resistance to antibiotics has clinically become a super challenge. Strategies to interrupt QS pathways by natural and synthetic QS inhibitors or quorum quenchers or analogs provide a potential treatment. We highlight the advancements in discovery of promising new targets for development of next generation antimicrobials to control infections caused by multidrug resistant bacterial pathogens.
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Topical term or geographic name entry element ANTIMICROBIALS
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Topical term or geographic name entry element AUTOINDUCERS
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Topical term or geographic name entry element QUORUM QUENCHING
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Topical term or geographic name entry element QUORUM SENSING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SIGNAL TRANSDUCTION
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Topical term or geographic name entry element VIRULENCE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Haque,S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yadav, D.K.
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Personal name Bisht, S.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yadav,N.
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Personal name Singh,V.
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Personal name Dubey, K.K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Dar, S.A.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1BIrQG-vZK9dxIMEehEgWDP3JVciAuFwT/view?usp=drivesdk">https://drive.google.com/file/d/1BIrQG-vZK9dxIMEehEgWDP3JVciAuFwT/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-17830 25.06.2025 25.06.2025 Documentos solicitados